(S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

Base Information

Chemical Name:(S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid
CAS No.:126111-16-8
Molecular Formula:C₁₉H₂₇NO₆
Molecular Weight:365.426
Hs Code.:

Synonyms:(S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

Suppliers and Price of (S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

There total 1 articles about (S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59221-35-1
(S)-6-[[(Phenylmethoxy)carbonyl]amino]-2-hydroxyhexanoic acid

: 3282-30-2
pivaloyl chloride

: 126111-16-8
(S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

Guidance literature:: With dmap; triethylamine; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1021/jm00167a028

Reference yield:

: 126111-16-8
(S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

: 117085-60-6
*,R^*)>-2,3-dihydro-1-<6-amino-2-<oxy>-1-oxohexyl>-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1: triethylamine, 4-(dimethylamino)pyridine / tetrahydrofuran / 16 h / Ambient temperature

2: 1.0 N LiOH / dioxane / 16 h / Ambient temperature

3: ethyl acetate / 1.5 h / Ambient temperature

4: N,N'-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / tetrahydrofuran / 2 h / Ambient temperature

5: NaIO₄ / dioxane; H₂O / 16 h / Ambient temperature

6: H₂ / 20percent Pd(OH)2/C / methanol / 2 h

With dmap; lithium hydroxide; sodium periodate; hydrogen; triethylamine; dicyclohexyl-carbodiimide; palladium dihydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; water; ethyl acetate;
DOI:10.1021/jm00167a028

Reference yield:

: 126111-16-8
(S)-6-Benzyloxycarbonylamino-2-(2,2-dimethyl-propionyloxy)-hexanoic acid

: (S)-1-((S)-6-Benzyloxycarbonylamino-2-hydroxy-hexanoyl)-2,3-dihydro-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine, 4-(dimethylamino)pyridine / tetrahydrofuran / 16 h / Ambient temperature

2: 1.0 N LiOH / dioxane / 16 h / Ambient temperature

With dmap; lithium hydroxide; triethylamine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1021/jm00167a028