azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide

Base Information

• Chemical Name: azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide
• CAS No.: 1198110-27-8
• Molecular Formula: C₄₆H₆₅N₁₁O₉
• Molecular Weight: 916.09
• Mol file: 1198110-27-8.mol

Synonyms:azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide

Chemical Property of azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide

There total 1 articles about azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Glu(OH)-propargyl amide (1198110-28-9) + Fmoc-Val-OH (68858-20-8) + Fmoc-Leu-OH (35661-60-0) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (35661-39-3,136132-75-7) + N-Fmoc L-Phe (35661-40-6) + (S)-2-azido-6-((tert-butoxycarbonyl)amino)hexanoic acid (333366-32-8) → azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide (1198110-27-8)

Guidance literature:

Fmoc-Glu(OH)-propargyl amide; With 2-chlorotrityl chloride polystyrene resin; N-ethyl-N,N-diisopropylamine; at 20 ℃; for 16h; solid phase reaction;

With methanol; In dichloromethane; at 20 ℃; for 0.333333h; solid phase reaction;

Fmoc-Val-OH; Fmoc-Leu-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; N-Fmoc L-Phe; (S)-2-azido-6-((tert-butoxycarbonyl)amino)hexanoic acid; Further stages;

DOI:10.1039/b912851d

Reference yield: 15.0%

azido-Lys-Leu-Val-Phe-Phe-Ala-Glu-propargyl amide (1198110-27-8) → C46H67N11O9 + C92H130N22O18 (1198110-30-3)

Guidance literature:

With copper (I) acetate; In dimethyl sulfoxide; at 100 ℃; for 0.5h; Inert atmosphere; Microwave irradiation;

DOI:10.1039/b912851d

upstream raw materials:

Fmoc-Glu(OH)-propargyl amide

Fmoc-Val-OH

Fmoc-Leu-OH

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Downstream raw materials:

C₉₂H₁₃₀N₂₂O₁₈