1-[2-(4-Ureidophenoxy)ethyl]imidazole

Base Information

Chemical Name:1-[2-(4-Ureidophenoxy)ethyl]imidazole
CAS No.:75912-85-5
Molecular Formula:C₁₂H₁₄N₄O₂
Molecular Weight:246.269
Hs Code.:
ChEMBL ID:CHEMBL33151
DSSTox Substance ID:DTXSID701256754
Pharos Ligand ID:Y8S7BHNJG8Q2

Synonyms:CHEMBL33151;1-[2-(4-ureidophenoxy)ethyl]imidazole;SCHEMBL10747686;OXHACLMEJBRYLE-UHFFFAOYSA-N;DTXSID701256754;BDBM50026007;75912-85-5;[4-(2-Imidazol-1-yl-ethoxy)-phenyl]-urea;N-[4-[2-(1H-Imidazol-1-yl)ethoxy]phenyl]urea

Suppliers and Price of 1-[2-(4-Ureidophenoxy)ethyl]imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[2-(4-Ureidophenoxy)ethyl]imidazole

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:246.11167570
Heavy Atom Count:18
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)N)OCCN2C=CN=C2

Technology Process of 1-[2-(4-Ureidophenoxy)ethyl]imidazole

There total 4 articles about 1-[2-(4-Ureidophenoxy)ethyl]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.5%

: potassium cyanate

: 75912-83-3
4-(2-imidazol-1-yl-ethoxy)-phenylamine

: 75912-85-5
<4-<2-(1H-imidazol-1-yl)ethoxy>phenyl>urea

Guidance literature:: With hydrogenchloride; In water; for 0.25h; Ambient temperature;
DOI:10.1021/jm00148a009

Reference yield:

: 75912-83-3
4-(2-imidazol-1-yl-ethoxy)-phenylamine

: 75912-85-5
<4-<2-(1H-imidazol-1-yl)ethoxy>phenyl>urea

Guidance literature:: In hydrogenchloride; water;

Reference yield:

: 3383-72-0
1-(2-chloroethoxy)-4-nitrobenzene

: 75912-85-5
<4-<2-(1H-imidazol-1-yl)ethoxy>phenyl>urea

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) DMF, 100 deg C, 10 min, 2.) DMF, heating, 5.5 h

2: 69 percent / Fe, 5N aq. HCl / 0.33 h / Heating

3: 82.5 percent / 1N aq. HCl / H₂O / 0.25 h / Ambient temperature

With hydrogenchloride; iron; sodium hydride; In water;
DOI:10.1021/jm00148a009