C₁₄H₁₅ClO₃

Base Information

• Chemical Name: C₁₄H₁₅ClO₃
• CAS No.: 1027970-37-1
• Molecular Formula: C₁₄H₁₅ClO₃
• Molecular Weight: 266.724
• Mol file: 1027970-37-1.mol

Synonyms:C₁₄H₁₅ClO₃

Chemical Property of C₁₄H₁₅ClO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₅ClO₃

There total 3 articles about C₁₄H₁₅ClO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl (E)-3-(4-chlorophenyl)prop-2-enoate (24393-52-0) → C14H15ClO3 (1027970-37-1)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium hydroxide / tetrahydrofuran; ethanol; water / 4 h / 20 °C

2: triethylamine / tetrahydrofuran / 0.75 h / -10 °C

With triethylamine; lithium hydroxide; In tetrahydrofuran; ethanol; water;

DOI:10.1016/j.ejmech.2016.12.022

Reference yield:

3-(4-chlorophenyl)prop-2-enoic acid (1615-02-7,940-62-5) + pivaloyl chloride (3282-30-2) → C14H15ClO3 (1027970-37-1)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃; for 45h;

DOI:10.1016/j.ejmech.2012.09.014

Reference yield:

4-chlorobenzaldehyde (104-88-1) → C14H15ClO3 (1027970-37-1)

Guidance literature:

Multi-step reaction with 3 steps

1: dichloromethane / 16 h / 0 - 20 °C

2: lithium hydroxide / tetrahydrofuran; ethanol; water / 4 h / 20 °C

3: triethylamine / tetrahydrofuran / 0.75 h / -10 °C

With triethylamine; lithium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; water; 1: |Wittig Olefination;

DOI:10.1016/j.ejmech.2016.12.022

upstream raw materials:

3-(4-chlorophenyl)prop-2-enoic acid

pivaloyl chloride

4-chlorobenzaldehyde

ethyl (E)-3-(4-chlorophenyl)prop-2-enoate

Downstream raw materials:

(E)-1-(3-(4-chlorophenyl)prop-2-enoyl)-5,6-dihydropyridin-2(1H)-one