Technology Process of 3-bromo-2-tert-butylsulfanyl-4-iodobenzaldehyde oxime
There total 5 articles about 3-bromo-2-tert-butylsulfanyl-4-iodobenzaldehyde oxime which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydroxylamine hydrochloride;
In
ethanol; water;
for 2h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 1 h
2.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 80 °C / sealed tube
3.1: hydroxylamine hydrochloride / ethanol; water / 2 h / Reflux
With
hydroxylamine hydrochloride; potassium carbonate; lithium diisopropyl amide;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 1 h
2.1: hydrogen bromide / ethanol; water / 1.17 h / 20 - 60 °C
2.2: 0.25 h / 0 - 5 °C
2.3: 1 h / 80 °C
3.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
3.2: 1 h
4.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 80 °C / sealed tube
5.1: hydroxylamine hydrochloride / ethanol; water / 2 h / Reflux
With
hydroxylamine hydrochloride; hydrogen bromide; tert.-butyl lithium; potassium carbonate; lithium diisopropyl amide;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;
