cholesteryl 6-(4-nitrophenoxy)hexanoate

Base Information

• Chemical Name: cholesteryl 6-(4-nitrophenoxy)hexanoate
• CAS No.: 1107064-47-0
• Molecular Formula: C₃₉H₅₉NO₅
• Molecular Weight: 621.901
• Mol file: 1107064-47-0.mol

Synonyms:cholesteryl 6-(4-nitrophenoxy)hexanoate

Chemical Property of cholesteryl 6-(4-nitrophenoxy)hexanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cholesteryl 6-(4-nitrophenoxy)hexanoate

There total 4 articles about cholesteryl 6-(4-nitrophenoxy)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + cholesteryl ω-bromohexanoate (82962-33-2) → cholesteryl 6-(4-nitrophenoxy)hexanoate (1107064-47-0)

Guidance literature:

With potassium carbonate; In acetone; for 16h; Reflux;

DOI:10.1016/j.tet.2008.10.085

Reference yield:

6-bromohexanoyl chloride (22809-37-6) → cholesteryl 6-(4-nitrophenoxy)hexanoate (1107064-47-0)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / tetrahydrofuran / 12 h / 20 °C

2: potassium carbonate / acetone / 16 h / Reflux

With pyridine; potassium carbonate; In tetrahydrofuran; acetone;

DOI:10.1080/15421406.2010.504628

Reference yield:

cholesterol (57-88-5) → cholesteryl 6-(4-nitrophenoxy)hexanoate (1107064-47-0)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / tetrahydrofuran / 12 h / 20 °C

2: potassium carbonate / acetone / 16 h / Reflux

With pyridine; potassium carbonate; In tetrahydrofuran; acetone;

DOI:10.1080/15421406.2010.504628

upstream raw materials:

4-nitro-phenol

cholesteryl ω-bromohexanoate

6-bromohexanoyl chloride

cholesterol

Downstream raw materials:

cholesteryl 6-(4-aminophenoxy)hexanoate

C₃₉H₅₉N₃O₃

C₄₇H₆₅N₃O₃

C₄₇H₆₄N₄O₅