(4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

Base Information

Chemical Name:(4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide
CAS No.:298206-17-4
Molecular Formula:C₁₈H₁₆ClN₃O₃S
Molecular Weight:389.862
Hs Code.:

Synonyms:(4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

Suppliers and Price of (4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

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Technology Process of (4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

There total 1 articles about (4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 97651-28-0
ethyl 4-(4'-chlorophenyl)-3-cyano-6-methyl-1,2-dihydropyridine-5-carboxylate

: 79-07-2
Chloroacetamide

: 298206-17-4
(4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

Guidance literature:: With sodium acetate; In ethanol; for 3h; Heating;
DOI:10.1002/jhet.5570420606

Reference yield: 93.0%

: 298206-17-4
(4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

: 298206-19-6
3-amino-(4'-chlorophenyl)-5-ethoxycarbonyl-6-methylthieno[2,3-b]pyridine-2-carboxamide

Guidance literature:: With sodium ethanolate; In ethanol; for 0.0833333h; Heating;
DOI:10.1002/jhet.5570420606

Reference yield:

: 298206-17-4
(4-(4'-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-methyl)pyridin-2-ylthioacetamide

: ethyl 2,9-di(4'-chlorophenyl)-7-methyl-4-oxo-1,2,3,4-tetrahydropyrido[3',2':4,5]thieno[3,2-d]pyrimidine-8-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / sodium ethoxide / ethanol / 0.08 h / Heating

2: 88 percent / acetic acid / 3 h / Heating

With sodium ethanolate; In ethanol; acetic acid; 1: Thorpe-Ziegler cyclization;
DOI:10.1002/jhet.5570420606