N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide

Base Information

• Chemical Name: N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide
• CAS No.: 1617511-46-2
• Molecular Formula: C₂₇H₂₈N₂O₃
• Molecular Weight: 428.531
• Mol file: 1617511-46-2.mol

Synonyms:N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide

Chemical Property of N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide

There total 8 articles about N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

methanol (67-56-1) + (S)-2-{[3-(N-phthalimido)adamantan-1-yl]carboxamido}-3-phenylpropanoic acid (1617511-45-1) → (11R)-2,12-diaza-11-benzylpentacyclo[12.5.1.11,16.114,18.04,9]doeicosa-4,6,8-trien-3,10,13-trione + 2,12-diaza-10-methoxy-11-benzylpentacyclo[12.5.1.11,16.114,18.04,9]doeicosa-4,6,8-trien-3,13-dione + N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide (1617511-46-2)

Guidance literature:

(S)-2-{[3-(N-phthalimido)adamantan-1-yl]carboxamido}-3-phenylpropanoic acid; With potassium carbonate; In water; acetone; Inert atmosphere; UV-irradiation;

methanol; In dichloromethane; enantioselective reaction;

DOI:10.1016/j.tetlet.2014.05.118

Reference yield: 65.0%

methanol (67-56-1) + (R)-2-{[3-(N-phthalimido)adamantan-1-yl]carboxamido}-3-phenylpropanoic acid (1617511-49-5) → (11S)-2,12-diaza-11-benzylpentacyclo[12.5.1.11,16.114,18.04,9]doeicosa-4,6,8-trien-3,10,13-trione + 2,12-diaza-10-methoxy-11-benzylpentacyclo[12.5.1.11,16.114,18.04,9]doeicosa-4,6,8-trien-3,13-dione + N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide (1617511-46-2)

Guidance literature:

(R)-2-{[3-(N-phthalimido)adamantan-1-yl]carboxamido}-3-phenylpropanoic acid; With potassium carbonate; In water; acetone; Inert atmosphere; UV-irradiation;

methanol; In dichloromethane; enantioselective reaction;

DOI:10.1016/j.tetlet.2014.05.118

Reference yield: 10.0%

(S)-2-{[3-(N-phthalimido)adamantan-1-yl]carboxamido}-3-phenylpropanoic acid (1617511-45-1) → (11R)-2,12-diaza-11-benzylpentacyclo[12.5.1.11,16.114,18.04,9]doeicosa-4,6,8-trien-3,10,13-trione + N-[3-(2-phenylethan-1-yl)carbamoyladamantan-1-yl]phthalimide (1617511-46-2)

Guidance literature:

With potassium carbonate; In water; acetone; for 0.5h; Inert atmosphere; Irradiation;

DOI:10.5562/cca2482

upstream raw materials:

methanol

(S)-2-{[3-(N-phthalimido)adamantan-1-yl]carboxamido}-3-phenylpropanoic acid

(R)-2-{[3-(N-phthalimido)adamantan-1-yl]carboxamido}-3-phenylpropanoic acid

3-(N-phthalimido)-1-adamantane carboxylic acid