N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

Base Information

Chemical Name:N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate
CAS No.:1180486-31-0
Molecular Formula:C₂HF₃O₂*C₂₃H₂₅F₆N₃O₄S
Molecular Weight:667.55
Hs Code.:

Synonyms:N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

Suppliers and Price of N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

There total 7 articles about N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 474554-46-6
5,6-diethoxy-7-fluoro-3H-isoindol-1-ylamine

: 1178584-07-0
N-[3-(2-bromoacetyl)-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide

: 76-05-1
trifluoroacetic acid

: 1180486-31-0
N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

Guidance literature:: 5,6-diethoxy-7-fluoro-3H-isoindol-1-ylamine; N-[3-(2-bromoacetyl)-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide; In N,N-dimethyl-formamide; at 20 - 25 ℃; Inert atmosphere;

trifluoroacetic acid; In water; acetonitrile;

Reference yield:

: 1005514-86-2
3-dimethylamino-5-pentafluorosulfanylbenzoic acid

: 1180486-31-0
N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

Guidance literature:: Multi-step reaction with 7 steps

1.1: thionyl chloride / dichloromethane / 5 h / 20 °C / Reflux; Inert atmosphere

1.2: 1 h / Inert atmosphere

2.1: diethyl ether; tetrahydrofuran / 0 - 25 °C / Inert atmosphere

2.2: Cooling; Inert atmosphere

3.1: camphor-10-sulfonic acid / methanol / Inert atmosphere

4.1: phenyltrimethylammonium tribromide / tetrahydrofuran; methanol / 60 °C / Inert atmosphere

5.1: sulfuric acid / water / 4 h / 25 °C / Cooling with ice; Inert atmosphere

5.2: pH 8 / Cooling with ice

6.1: dichloromethane / Inert atmosphere

7.1: N,N-dimethyl-formamide / 20 - 25 °C / Inert atmosphere

With thionyl chloride; sulfuric acid; phenyltrimethylammonium tribromide; camphor-10-sulfonic acid; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 1005514-88-4
1-(3-dimethylamino-5-pentafluorosulfanylphenyl)ethanone

: 1180486-31-0
N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate

Guidance literature:: Multi-step reaction with 5 steps

1.1: camphor-10-sulfonic acid / methanol / Inert atmosphere

2.1: phenyltrimethylammonium tribromide / tetrahydrofuran; methanol / 60 °C / Inert atmosphere

3.1: sulfuric acid / water / 4 h / 25 °C / Cooling with ice; Inert atmosphere

3.2: pH 8 / Cooling with ice

4.1: dichloromethane / Inert atmosphere

5.1: N,N-dimethyl-formamide / 20 - 25 °C / Inert atmosphere

With sulfuric acid; phenyltrimethylammonium tribromide; camphor-10-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;