Acetonitrile, [1-(2-propynyl)-2-pyrrolidinylidene]-, (2E)- (9CI)

Base Information

Chemical Name:Acetonitrile, [1-(2-propynyl)-2-pyrrolidinylidene]-, (2E)- (9CI)
CAS No.:283166-93-8
Molecular Formula:C₉H₁₀N₂
Molecular Weight:146.192
Hs Code.:
Mol file:283166-93-8.mol

Synonyms:Acetonitrile,[1-(2-propynyl)-2-pyrrolidinylidene]-, (2E)- (9CI)

Suppliers and Price of Acetonitrile, [1-(2-propynyl)-2-pyrrolidinylidene]-, (2E)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Acetonitrile, [1-(2-propynyl)-2-pyrrolidinylidene]-, (2E)- (9CI)

Chemical Property:

PSA：27.03000
LogP:1.06078

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Acetonitrile, [1-(2-propynyl)-2-pyrrolidinylidene]-, (2E)- (9CI)

There total 2 articles about Acetonitrile, [1-(2-propynyl)-2-pyrrolidinylidene]-, (2E)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 35022-17-4
1-(2-propynyl)-2,3,4,5-dihydro-pyrrolo-2-thione

: 590-17-0
cyanomethyl bromide

: 283166-93-8
(E)-2-[1-(2-propynyl)-2,3,4,5-tetrahydro-pyrrol-2-ylidene]acetonitrile

Guidance literature:: 1-(2-propynyl)-2,3,4,5-dihydro-pyrrolo-2-thione; cyanomethyl bromide; In acetonitrile; at 20 ℃;

With triethylamine; triphenylphosphine; at 20 ℃;
DOI:10.1016/S0040-4039(00)00406-8

Reference yield:

: 766-61-0
1-prop-2-ynyl-pyrrolidin-2-one

: 283166-93-8
(E)-2-[1-(2-propynyl)-2,3,4,5-tetrahydro-pyrrol-2-ylidene]acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: 87 percent / P₂S₅; Na₂CO₃ / tetrahydrofuran / 20 °C

2.1: acetonitrile / 20 °C

2.2: 74 percent / Et₃N; Ph₃P / 20 °C

With tetraphosphorus decasulfide; sodium carbonate; In tetrahydrofuran; acetonitrile; 1.1: thiolation / 2.1: Alkylation / 2.2: Rearrangement;
DOI:10.1016/S0040-4039(00)00406-8

Reference yield: 19.0%

: 283166-93-8
(E)-2-[1-(2-propynyl)-2,3,4,5-tetrahydro-pyrrol-2-ylidene]acetonitrile

: 283166-91-6
7-oxo-1,2,3,7-tetrahydro-8-indolizinecarbonitrile

Guidance literature:: (E)-2-[1-(2-propynyl)-2,3,4,5-tetrahydro-pyrrol-2-ylidene]acetonitrile; With 9-borabicyclo[3.3.1]nonane dimer; In tetrahydrofuran; at 0 ℃; for 2h;

With benzo[1,3,2]dioxaborole; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

With potassium hydroxide; silver nitrate; at 0 - 20 ℃; for 1h;
DOI:10.1016/S0040-4039(00)00406-8