N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine

Base Information

• Chemical Name: N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine
• CAS No.: 281211-09-4
• Molecular Formula: C₁₂H₁₂Cl₃N₃
• Molecular Weight: 304.606
• Hs Code.: 2933990090
• Mol file: 281211-09-4.mol

Synonyms:2-(tert-Butylamino)-3,6,7-trichloroquinoxaline 96%;N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine;2-(N-t-Butylamino)-3,6,7-trichloroquinoxaline;3-(N-t-Butylamino)-2,6,7-trichloroquinoxaline;N-t-Butyl-3,6,7-trichloroquinoxalin-2-amine;2-(tert-Butylamino)-3,6,7-trichloroquinoxaline

Chemical Property of N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine

Chemical Property:

• Vapor Pressure: 2.13E-06mmHg at 25°C
• Refractive Index: 1.65
• Boiling Point: 393.4°Cat760mmHg
• Flash Point: 191.8°C
• PSA: 37.81000
• Density: 1.417g/cm³
• LogP: 4.87340

Purity/Quality:

97% ^*data from raw suppliers

2-(tert-Butylamino)-3,6,7-trichloroquinoxaline 96% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine

There total 2 articles about N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,6,7-tetrachloroquinoxaline (25983-14-6) + tert-butylamine (75-64-9) → (6,7-dichloro-3-[(1-methyl-1H-imidazol-2-yl)sulfonyl]quinoxalin-2-yl)tert-butylamine (281211-09-4)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmcl.2007.06.086

Reference yield:

→ (6,7-dichloro-3-[(1-methyl-1H-imidazol-2-yl)sulfonyl]quinoxalin-2-yl)tert-butylamine (281211-09-4)

Guidance literature:

Reference yield:

(6,7-dichloro-3-[(1-methyl-1H-imidazol-2-yl)sulfonyl]quinoxalin-2-yl)tert-butylamine (281211-09-4) + sodium methansulfinate (20277-69-4) → 6,7-dichloro-2-methylsulfonyl-3-(N-tert-butylamino)quinoxaline (281209-71-0)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 3h;

DOI:10.1016/j.bmcl.2007.06.086

upstream raw materials:

2,3,6,7-tetrachloroquinoxaline

tert-butylamine

Downstream raw materials:

6,7-dichloro-2-methylsulfonyl-3-(N-tert-butylamino)quinoxaline