Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate

Base Information

• Chemical Name: Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate
• CAS No.: 120697-90-7
• Molecular Formula: C₁₉H₂₈O₄
• Molecular Weight: 320.429
• Mol file: 120697-90-7.mol

Synonyms:Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate

Chemical Property of Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate

There total 1 articles about Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl bromide (100-39-0) + Methyl (1S,3R)-1-hydroxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate (120697-89-4) → Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate (120697-90-7)

Guidance literature:

With potassium hydride; Yield given. Multistep reaction; 1.) THF, 0 deg C, 2.) 0 deg C, 22 h;

DOI:10.1055/s-1988-27769

Reference yield: 91.0%

Methyl (1S,3R)-1-benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate (120697-90-7) → (1S,3R)-1-Benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylic acid (120697-91-8)

Guidance literature:

With sodium hydroxide; In methanol; at 130 ℃; for 20h;

DOI:10.1055/s-1988-27769

upstream raw materials:

benzyl bromide

Methyl (1S,3R)-1-hydroxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylate

Downstream raw materials:

(1S,3R)-1-Benzyloxy-3-methoxymethyl-2,2,3-trimethylcyclopentanecarboxylic acid