8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

Base Information

Chemical Name:8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine
CAS No.:148474-66-2
Molecular Formula:C₂₃H₂₁N₅S
Molecular Weight:399.519
Hs Code.:

Synonyms:8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

Suppliers and Price of 8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

There total 6 articles about 8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 75-15-0,12122-00-8
carbon disulfide

: 148474-44-6
5-<(2'-cyanobiphenyl-4-yl)methyl>-4-hydrazino-2-methyl-6-n-propylpyrimidine

: 148474-66-2
8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

Guidance literature:: In butan-1-ol; for 3h; Heating;
DOI:10.1021/jm00041a016

Reference yield:

: 114772-54-2
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

: 148474-66-2
8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1: (i-Pr)2NEt, LiCl / tetrahydrofuran / 15 h / Heating

2: 1.) MeONa / 1.) MeOH, RT, 15 min, 2.) MeOH, a) RT, 20 h, b) reflux, 3 h

3: 98 percent / POCl₃ / 6 h / 100 °C

4: 92 percent / N₂H₄ / ethanol / 2 h / Heating

5: 86 percent / butan-1-ol / 3 h / Heating

With sodium methylate; N-ethyl-N,N-diisopropylamine; lithium chloride; hydrazine; trichlorophosphate; In tetrahydrofuran; ethanol; butan-1-ol;
DOI:10.1021/jm00041a016

Reference yield:

: 3249-68-1
ethyl butyroyl acetate

: 148474-66-2
8-<(2'-cyanobiphenyl-4-yl)methyl>-2-mercapto-5-methyl-7-n-propyl-<1,2,4>-triazolo<1,5-c>pyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1: (i-Pr)2NEt, LiCl / tetrahydrofuran / 15 h / Heating

2: 1.) MeONa / 1.) MeOH, RT, 15 min, 2.) MeOH, a) RT, 20 h, b) reflux, 3 h

3: 98 percent / POCl₃ / 6 h / 100 °C

4: 92 percent / N₂H₄ / ethanol / 2 h / Heating

5: 86 percent / butan-1-ol / 3 h / Heating

With sodium methylate; N-ethyl-N,N-diisopropylamine; lithium chloride; hydrazine; trichlorophosphate; In tetrahydrofuran; ethanol; butan-1-ol;
DOI:10.1021/jm00041a016