7α-bromocholest-5-en-3β-ol benzoate

Base Information

• Chemical Name: 7α-bromocholest-5-en-3β-ol benzoate
• CAS No.: 26048-46-4
• Molecular Formula: C₃₄H₄₉BrO₂
• Molecular Weight: 569.666
• Mol file: 26048-46-4.mol

Synonyms:7α-bromocholest-5-en-3β-ol benzoate

Chemical Property of 7α-bromocholest-5-en-3β-ol benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7α-bromocholest-5-en-3β-ol benzoate

There total 15 articles about 7α-bromocholest-5-en-3β-ol benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

cholesteryl benzoate (604-32-0) → 7α-bromocholest-5-en-3β-ol benzoate (26048-46-4)

Guidance literature:

With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; In hexane; for 0.5h; Heating;

Reference yield:

3β,7β-cholest-5-ene-3,7-diol-3-benzoate (17974-80-0) → 7α-bromocholest-5-en-3β-ol benzoate (26048-46-4)

Guidance literature:

With pyridine; diethyl ether; phosphorus tribromide;

Reference yield:

7β-bromocholest-5-en-3β-ol benzoate (65942-28-1) → 7α-bromocholest-5-en-3β-ol benzoate (26048-46-4)

Guidance literature:

With acetone;

DOI:10.1021/ja01521a053 DOI:10.1002/hlca.19510340416

upstream raw materials:

tetrachloromethane

N-Bromosuccinimide

cholesteryl benzoate

diethyl ether

Downstream raw materials:

7β-bromocholest-5-en-3β-ol benzoate

7β-acetylcholesteryl benzoate

3β-benzoyloxy-cholesta-5,8-diene

7α-iodocholesterol benzoate

Refernces

• 1、 Schaltegger. "-". . . Retrieved 1950.
• 2、 Yakhimovich, R. I.,Ponomarev, N. E.,Dvorko, G. F.. "KINETICS AND MECHANISM OF THE UNIMOLECULAR HETEROLYSIS OF INDUSTRIAL ORGANOHALOGEN COMPOUNDS. IV. DEHYDROBROMINATION OF 7α-BROMOCHOLESTEROL BENZOATE IN AROMATIC SOLVENTS, IN CHLOROFORM, AND IN 1,1,1-TRICHLOROETHANE". . p. 781 - 785. Retrieved 2007/10/02.