3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane

Base Information

• Chemical Name: 3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane
• CAS No.: 58028-15-2
• Molecular Formula: C₂₇H₄₅IO₂
• Molecular Weight: 528.558
• Mol file: 58028-15-2.mol

Synonyms:3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane

Chemical Property of 3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane

There total 5 articles about 3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.2%

cholesterol (57-88-5) → 3-formyloxy-2-iodo-A-nor-2,3-secocholest-5-ene (77524-09-5) + 3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane (58028-15-2) + 5beta,6beta-Epoxycholestanol (2953-38-0,4025-59-6,24116-45-8,55700-78-2,75764-48-6,97100-48-6,114246-94-5,134356-45-9,1250-95-9) + 5α,6α-epoxycholestan-3β-ol (1250-95-9)

Guidance literature:

With iodine; mercury(II) oxide; In tetrachloromethane; for 1h; Further byproducts given. Yields of byproduct given; Irradiation; substrate-HgO-I₂ ratio= 1:5:5;

DOI:10.1016/S0040-4020(01)80855-3

Reference yield: 27.0%

cholesterol (57-88-5) → cholestanetriol (1253-84-5) + 3-formyloxy-2-iodo-A-nor-2,3-secocholest-5-ene (77524-09-5) + 3α,5-epoxy-6β-iodo-A-homo-4-oxa-5α-cholestane (58028-14-1) + 3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane (58028-15-2)

Guidance literature:

With iodine; mercury(II) oxide; In benzene; for 9h; Product distribution; Irradiation; heat at 55 - 60 deg C, other times;

DOI:10.1039/P19810000236

Reference yield:

epicholesterol (474-77-1) → cholestanetriol (1253-84-5) + 3-formyloxy-2-iodo-A-nor-2,3-secocholest-5-ene (77524-09-5) + 3α,5-epoxy-6β-iodo-A-homo-4-oxa-5α-cholestane (58028-14-1) + 3α,5-epoxy-6α-iodo-A-homo-4-oxa-5α-cholestane (58028-15-2)

Guidance literature:

With iodine; mercury(II) oxide; In benzene; for 5h; Product distribution; Irradiation;

DOI:10.1039/P19810000236

upstream raw materials:

epicholesterol

cholesterol