methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate

Base Information

• Chemical Name: methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate
• CAS No.: 1193340-93-0
• Molecular Formula: C₁₉H₁₆O₇
• Molecular Weight: 356.332
• Mol file: 1193340-93-0.mol

Synonyms:methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate

Chemical Property of methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate

There total 1 articles about methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acrylic acid (79-10-7) + methyl 6-iodo-4-(phenylmethoxy)-2H-benzo1,3-dioxolene-5-carboxylate → methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate (1193340-93-0)

Guidance literature:

With tributyl-amine; palladium diacetate; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 100 ℃; for 2.5h; Inert atmosphere;

DOI:10.1002/ejoc.200900719

Reference yield: 95.0%

methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate (1193340-93-0) → methyl (E)-4-(benzyloxy)-6-(3-hydroxyprop-1-enyl)-1,3-benzodioxole-5-carboxylate (1193340-94-1)

Guidance literature:

methyl (E)-4-(benzyloxy)-6-(2-carboxyvinyl)-1,3-benzodioxole-5-carboxylate; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at -6 - -2 ℃; Inert atmosphere;

With sodium tetrahydroborate; In tetrahydrofuran; Triethylene glycol dimethyl ether; water; at 0 - 1 ℃; Inert atmosphere;

DOI:10.1002/ejoc.200900719

upstream raw materials:

acrylic acid

Downstream raw materials:

methyl (E)-4-(benzyloxy)-6-(3-hydroxyprop-1-enyl)-1,3-benzodioxole-5-carboxylate