Acetic acid, fluoronitro-, ethyl ester (7CI,8CI,9CI)

Base Information

• Chemical Name: Acetic acid, fluoronitro-, ethyl ester (7CI,8CI,9CI)
• CAS No.: 3620-16-4
• Molecular Formula: C4H6 F N O4
• Molecular Weight: 151.094
• Mol file: 3620-16-4.mol

Synonyms:Aceticacid, fluoronitro-, ethyl ester (7CI,8CI,9CI); Ethyl 2-fluoro-2-nitroacetate;Ethyl fluoronitroacetate

Chemical Property of Acetic acid, fluoronitro-, ethyl ester (7CI,8CI,9CI)

Chemical Property:

• Boiling Point: 85 °C
• PSA: 72.12000
• LogP: 0.64500

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetic acid, fluoronitro-, ethyl ester (7CI,8CI,9CI)

There total 7 articles about Acetic acid, fluoronitro-, ethyl ester (7CI,8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

nitroacetic acid ethyl ester (626-35-7) → ethyl 2-fluoro-2-nitroacetate (3620-16-4) + ethyl 2,2-difluoro-2-nitroacetate (680-69-3)

Guidance literature:

With fluorine; cuprous nitrate; In acetonitrile; at 5 ℃; for 4h;

DOI:10.1016/S0022-1139(98)00254-1

Reference yield: 52.0%

nitroacetic acid ethyl ester (626-35-7) → ethyl 2-fluoro-2-nitroacetate (3620-16-4)

Guidance literature:

Reference yield: 34.5%

ethanol (64-17-5) + trans-1,2-difluorodinitroethylene (131153-10-1) → ethyl 2-fluoro-2-nitroacetate (3620-16-4)

Guidance literature:

for 3h; Heating;

DOI:10.1021/jo00002a011

upstream raw materials:

ethanol

Fluor-nitro-essigsaeure-chlorid

diethyl 2-fluoro-2-nitromalonate

trans-1,2-difluorodinitroethylene