({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

Base Information

Chemical Name:({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester
CAS No.:103497-73-0
Molecular Formula:C₃₅H₄₁N₃O₁₃
Molecular Weight:711.723
Hs Code.:

({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

Synonyms:({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

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Chemical Property of ({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

Chemical Property:

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Technology Process of ({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

There total 1 articles about ({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20627-73-0
1-(dimethoxymethyl)-2-nitrobenzene

: 96315-10-5
N-(2-(2-(2-(bis(methoxycarbonylmethyl)amino)phenoxy)ethoxy)-4-methylphenyl)-N-(methoxycarbonylmethyl)aminoacetic acid methyl ester

: 103497-73-0
({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

Guidance literature:: With 2,6-di-tert-butyl-pyridine; trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; Yield given. Multistep reaction; 1.) CHCl₃, room temp.; 2.) CHCl₃, room temp., 15 min.;
DOI:10.1021/ja00218a034

Reference yield:

: 103497-73-0
({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

: 103471-61-0
({2-{2-[2-(Bis-carboxymethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-carboxymethyl-amino)-acetic acid

Guidance literature:: With potassium hydroxide; In 1,4-dioxane; methanol; water;
DOI:10.1021/ja00218a034

Reference yield:

: 103497-73-0
({2-{2-[2-(Bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-[methoxy-(2-nitro-phenyl)-methyl]-phenyl}-methoxycarbonylmethyl-amino)-acetic acid methyl ester

: 103497-72-9
{[2-{2-[2-(Bis-carboxymethyl-amino)-5-methyl-phenoxy]-ethoxy}-4-(2-nitroso-benzoyl)-phenyl]-carboxymethyl-amino}-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1M KOH then acid / dioxane; methanol; H₂O

2: KCl, Tris, MOPS, K₂H₂EGTA, HCl / H₂O / 22 °C / Irradiation

With hydrogenchloride; 3-(N-morpholino)propanesulfonic acid; potassium hydroxide; K₂H₂EGTA; potassium chloride; 2-amino-2-hydroxymethyl-1,3-propanediol; In 1,4-dioxane; methanol; water;
DOI:10.1021/ja00218a034