1,3'-Bipyrrolidine

Base Information

• Chemical Name: 1,3'-Bipyrrolidine
• CAS No.: 267241-99-6
• Molecular Formula: C8H16 N2
• Molecular Weight: 140.23
• Hs Code.: 2933990090
• European Community (EC) Number: 859-314-9
• DSSTox Substance ID: DTXSID30562383
• Mol file: 267241-99-6.mol

Synonyms:1,3'-bipyrrolidine;267241-99-6;1-pyrrolidin-3-ylpyrrolidine;1,3-Bipyrrolidine(9CI);[1,3']Bipyrrolidinyl;1-(pyrrolidin-3-yl)pyrrolidine;MFCD06740353;Butylpropionate;3-(pyrrolidino)pyrrolidine;3-pyrrolidin-yl-pyrrolidine;SCHEMBL223255;1-(3-pyrrolidinyl)-pyrrolidine;DTXSID30562383;HFZLSTDPRQSZCQ-UHFFFAOYSA-N;ZB1823;AKOS004121497;AKOS016344027;SB45767;SB46860;BS-52959;CS-0216815;EN300-61758;F53557;A818569;Z970090326

Chemical Property of 1,3'-Bipyrrolidine

Chemical Property:

• Boiling Point: 215.5±8.0 °C(Predicted)
• PKA: 10.28±0.20(Predicted)
• Flash Point: 91.547oC
• PSA: 15.27000
• Density: 1.014±0.06 g/cm3(Predicted)
• LogP: 2.31480
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 140.131348519
• Heavy Atom Count: 10
• Complexity: 108

Purity/Quality:

98%min ^*data from raw suppliers

1,3''-bipyrrolidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCN(C1)C2CCNC2

Technology Process of 1,3'-Bipyrrolidine

There total 1 articles about 1,3'-Bipyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H24N2O2 (1215039-65-8) → 4-pyrrolidinopyrrolidine (267241-99-6,900164-95-6)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 3h;

DOI:10.1016/j.bmcl.2009.11.122

Reference yield:

4-pyrrolidinopyrrolidine (267241-99-6,900164-95-6) + C19H23N3O5 (1608129-77-6) → C13H24N2O2 (1215039-65-8) + [1,3']bipyrrolidinyl-1'-carboxylic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide (1608129-54-9)

Guidance literature:

In 1,4-dioxane; at 60 ℃; for 6h;

DOI:10.1016/j.ejmech.2014.03.031

Reference yield:

formic acid (64-18-6) + 4-pyrrolidinopyrrolidine (267241-99-6,900164-95-6) + C19H21F2N3O5 (1608129-78-7) → C13H24N2O2 (1215039-65-8) + [1,3']bipyrrolidinyl-1'-carboxylic acid [5-(2-difluoromethoxyphenyl)-2H-pyrazol-3-yl]amide formate salt

Guidance literature:

4-pyrrolidinopyrrolidine; C₁₉H₂₁F₂N₃O₅; In 1,4-dioxane; at 60 ℃; for 6h;

formic acid; In water; acetonitrile; for 0.166667h;

DOI:10.1016/j.ejmech.2014.03.031

upstream raw materials:

C₁₃H₂₄N₂O₂

Downstream raw materials:

C₁₃H₂₄N₂O₂

[1,3']bipyrrolidinyl-1'-carboxylic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide

C₁₈H₂₇N₃O

Refernces