1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Base Information

Chemical Name:1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione
CAS No.:95782-34-6
Molecular Formula:C₃₄H₄₅N₃O₆S₂Si
Molecular Weight:683.965
Hs Code.:

Synonyms:1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Suppliers and Price of 1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

There total 4 articles about 1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 124-63-0
methanesulfonyl chloride

: 95782-32-4
1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-(hydroxymethyl)-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

: 95782-34-6
1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Guidance literature:: With triethylamine; In tetrahydrofuran; for 0.166667h; Ambient temperature;
DOI:10.1021/ja00297a035

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 95782-34-6
1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 2 steps

1: 46 percent / DMAP, triethylamine / CH₂Cl₂ / 24 h / Ambient temperature

2: 98 percent / Et₃N / tetrahydrofuran / 0.17 h / Ambient temperature

With dmap; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja00297a035

Reference yield:

: 95782-30-2
1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-(hydroxymethyl)-3''-(hydroxypropyl)>-2,5-piperazinedione

: 95782-34-6
1,4-dibenzyl-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 2 steps

1: 46 percent / DMAP, triethylamine / CH₂Cl₂ / 24 h / Ambient temperature

2: 98 percent / Et₃N / tetrahydrofuran / 0.17 h / Ambient temperature

With dmap; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja00297a035