Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

Base Information

Chemical Name:Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester
CAS No.:831235-43-9
Molecular Formula:C₄₄H₆₂O₆SSi
Molecular Weight:747.124
Hs Code.:

Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

Synonyms:Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

Suppliers and Price of Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

There total 2 articles about Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 124-63-0
methanesulfonyl chloride

: 831235-42-8
(R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-Butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butan-1-ol

: 831235-43-9
Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 ℃; for 3h;
DOI:10.1021/jo048456c

Reference yield:

: (1R,3S,4aR,5R,8aS)-5-[(R)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-methyl-propyl]-3-(tert-butyl-diphenyl-silanyloxy)-1-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-7-methyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalene

: 831235-43-9
Methanesulfonic acid (R)-2-{(1R,4aS,5R,7S,8aR)-7-(tert-butyl-diphenyl-silanyloxy)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-3-methyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-methyl-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / TsOH / tetrahydrofuran; methanol / 3 h / 20 °C

2: 98 percent / Et₃N; DMAP / CH₂Cl₂ / 3 h / 0 °C

With dmap; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo048456c