benzylidene-(3-chloro-benzyl)-amine

Base Information

• Chemical Name: benzylidene-(3-chloro-benzyl)-amine
• CAS No.: 67907-54-4
• Molecular Formula: C₁₄H₁₂ClN
• Molecular Weight: 229.709
• Mol file: 67907-54-4.mol

Synonyms:benzylidene-(3-chloro-benzyl)-amine

Chemical Property of benzylidene-(3-chloro-benzyl)-amine

Chemical Property:

Purity/Quality:

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Technology Process of benzylidene-(3-chloro-benzyl)-amine

There total 5 articles about benzylidene-(3-chloro-benzyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

m-chlorobenzylamine (4152-90-3) + benzyl alcohol (100-51-6,185532-71-2) → benzylidene-(3-chloro-benzyl)-amine (67907-54-4)

Guidance literature:

With cobalt(II)(2,6-bis(morpholinomethyl)pyridine)bromide; potassium tert-butylate; In octane; at 150 ℃; for 32h; Molecular sieve;

DOI:10.1039/c8cy00859k

Reference yield: 20.0%

m-chlorobenzylamine (4152-90-3) + benzyl alcohol (100-51-6,185532-71-2) → benzylidene-(3-chloro-benzyl)-amine (67907-54-4) + N-(3-chlorobenzyl) benzamide + benzaldehyde (100-52-7)

Guidance literature:

With C₂₆H₃₆ClN₂RuS⁽¹⁺⁾*F₆P^(1-); caesium carbonate; In toluene; at 125 ℃; for 36h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejic.202101033

Reference yield:

3-chlorobenzaldehyde oxime (34158-71-9) → benzylidene-(3-chloro-benzyl)-amine (67907-54-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium-amalgam; acetic acid

With sodium amalgam; acetic acid;

DOI:10.1039/jr9320000696

upstream raw materials:

3-chlorobenzaldehyde N-benzylimine

sodium ethanolate

benzaldehyde

m-chlorobenzylamine

Downstream raw materials:

3-chlorobenzaldehyde N-benzylimine