3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

Base Information

Chemical Name:3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one
CAS No.:1445137-23-4
Molecular Formula:C₂₄H₂₆N₄O₂
Molecular Weight:402.496
Hs Code.:

Synonyms:3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

Suppliers and Price of 3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

There total 3 articles about 3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 931-53-3
Cyclohexyl isocyanide

: 1445137-10-9
4-amino-6-methylphthalazin-1(2H)-one

: 123-11-5
4-methoxy-benzaldehyde

: 1445137-23-4
3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

Guidance literature:: With toluene-4-sulfonic acid; In dimethyl sulfoxide; at 70 ℃; for 20h; Schlenk technique; Inert atmosphere;
DOI:10.1021/jo401131p

Reference yield:

: 191104-16-2
2-(trifluoromethanesulfonyloxy)4-methylbenzoic acid methyl ester

: 1445137-23-4
3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / dimethyl sulfoxide / 0.08 h / 150 °C / Inert atmosphere; Microwave irradiation; Sealed tube

2: tetrafluoroboric acid / water; butan-1-ol / 0.33 h / 160 °C / Microwave irradiation

3: toluene-4-sulfonic acid / dimethyl sulfoxide / 20 h / 70 °C / Schlenk technique; Inert atmosphere

With tetrafluoroboric acid; palladium diacetate; toluene-4-sulfonic acid; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In water; dimethyl sulfoxide; butan-1-ol;
DOI:10.1021/jo401131p

Reference yield:

: 1346229-12-6
4-(tert-butylamino)-6-methylphthalazin-1(2H)-one

: 1445137-23-4
3-(cyclohexylamino)-2-(4-methoxyphenyl)-9-methylimidazo-[2,1-a]phthalazin-6(5H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: tetrafluoroboric acid / water; butan-1-ol / 0.33 h / 160 °C / Microwave irradiation

2: toluene-4-sulfonic acid / dimethyl sulfoxide / 20 h / 70 °C / Schlenk technique; Inert atmosphere

With tetrafluoroboric acid; toluene-4-sulfonic acid; In water; dimethyl sulfoxide; butan-1-ol;
DOI:10.1021/jo401131p