Carbamic acid, 2-pyrimidinyl-, 1,1-dimethylethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, 2-pyrimidinyl-, 1,1-dimethylethyl ester (9CI)
• CAS No.: 264600-81-9
• Molecular Formula: C₉H₁₃N₃O₂
• Molecular Weight: 195.221
• Mol file: 264600-81-9.mol

Synonyms:Carbamic acid, 2-pyrimidinyl-, 1,1-dimethylethyl ester (9CI)

Chemical Property of Carbamic acid, 2-pyrimidinyl-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

• PSA: 64.11000
• LogP: 1.89660

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, 2-pyrimidinyl-, 1,1-dimethylethyl ester (9CI)

There total 2 articles about Carbamic acid, 2-pyrimidinyl-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2-aminopyrimidine (109-12-6) + di-tert-butyl dicarbonate (24424-99-5) → 1,1-dimethylethyl 2-pyrimidyl carbamate (264600-81-9)

Guidance literature:

In tert-butyl alcohol; at 20 ℃; for 48h;

DOI:10.1021/jo025554u

Reference yield:

→ 1,1-dimethylethyl 2-pyrimidyl carbamate (264600-81-9)

Guidance literature:

Reference yield: 40.0%

1,1-dimethylethyl 2-pyrimidyl carbamate (264600-81-9) + methyl iodide (74-88-4) → tert-butyl N-methyl-N-(2-pyrimidyl)carbamate (436161-78-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 0.5h;

DOI:10.1021/jo025554u

upstream raw materials:

2-aminopyrimidine

di-tert-butyl dicarbonate

Downstream raw materials:

tert-butyl N-methyl-N-(2-pyrimidyl)carbamate