2-chloro-N-(pyridin-2-yl)benzenesulfonamide

Base Information

Chemical Name:2-chloro-N-(pyridin-2-yl)benzenesulfonamide
CAS No.:339292-55-6
Molecular Formula:C₁₁H₉ClN₂O₂S
Molecular Weight:268.724
Hs Code.:
DSSTox Substance ID:DTXSID301275887

Synonyms:339292-55-6;2-chloro-N-(pyridin-2-yl)benzenesulfonamide;Benzenesulfonamide, 2-chloro-N-2-pyridinyl-;2-chloro-N-pyridin-2-ylbenzenesulfonamide;Oprea1_258807;SCHEMBL16110825;DTXSID301275887;STK753352;2-Chloro-N-2-pyridinylbenzenesulfonamide

Suppliers and Price of 2-chloro-N-(pyridin-2-yl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-chloro-N-(pyridin-2-yl)benzenesulfonamide

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:268.0073264
Heavy Atom Count:17
Complexity:342

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)S(=O)(=O)NC2=CC=CC=N2)Cl

Technology Process of 2-chloro-N-(pyridin-2-yl)benzenesulfonamide

There total 1 articles about 2-chloro-N-(pyridin-2-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 504-29-0
2-aminopyridine

: 2905-23-9
2-chlorophenylsulfonyl chloride

: 339292-55-6
2-chloro-N-(pyridin-2-yl)benzenesulfonamide

Guidance literature:: With pyridine; for 4h; Reflux;
DOI:10.1016/j.tet.2011.06.063

Reference yield:

: 339292-55-6
2-chloro-N-(pyridin-2-yl)benzenesulfonamide

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: tert-butyl 4-((2-chloro-N-(pyridin-2-yl)phenyl)sulfonamido)piperidine-1-carboxylate

Guidance literature:: 2-chloro-N-(pyridin-2-yl)benzenesulfonamide; t-butyl 4-hydroxy piperidine-1-carboxylate; With triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 0.166667h;

With di-isopropyl azodicarboxylate; In tetrahydrofuran; at 20 ℃; for 48h;

Reference yield:

: 339292-55-6
2-chloro-N-(pyridin-2-yl)benzenesulfonamide

: 2-chloro-N-(1-((4-ethylphenyl)sulfonyl)piperidin-4-yl)-N-(pyridin-2-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triphenylphosphine / tetrahydrofuran / 0.17 h / 0 °C

1.2: 48 h / 20 °C

2.1: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C

3.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 20 °C

With N-ethyl-N,N-diisopropylamine; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;