1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine

Base Information

Chemical Name:1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine
CAS No.:1258233-00-9
Molecular Formula:C₂₈H₃₀BFN₂O₄
Molecular Weight:488.367
Hs Code.:

Synonyms:1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine

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Chemical Property of 1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine

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Technology Process of 1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine

There total 4 articles about 1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: (1,1'-bis(diphenylphosphino)ferrocene)dichloropalladium

: 1258232-99-3
2-(4-bromophenyl)-1-(4-fluorophenyl)-5-(4-nitrophenyl)pyrrolidine

: 73183-34-3
bis(pinacol)diborane

: 7440-18-8
ruthenium

: 1258233-00-9
1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine

Guidance literature:: With nitrogen; potassium acetate; In 1,4-dioxane; hexane; ethyl acetate;

Reference yield:

: 1258232-96-0
1-(4-bromophenyl)-4-(4-nitrophenyl)butane-1,4-dione

: 1258233-00-9
1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium borohydrid / ethanol; ethyl acetate

2: dichloromethane; triethylamine

3: hydrogenchloride / methanol; N,N-dimethyl-formamide

4: nitrogen; potassium acetate / 1,4-dioxane; hexane; ethyl acetate

With hydrogenchloride; sodium borohydrid; nitrogen; potassium acetate; In 1,4-dioxane; methanol; ethanol; hexane; dichloromethane; ethyl acetate; triethylamine; N,N-dimethyl-formamide;

Reference yield:

: 1258232-97-1
1-(4-bromophenyl)-4-(4-nitrophenyl)butane-1,4-diol

: 1258233-00-9
1-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane; triethylamine

2: hydrogenchloride / methanol; N,N-dimethyl-formamide

3: nitrogen; potassium acetate / 1,4-dioxane; hexane; ethyl acetate

With hydrogenchloride; nitrogen; potassium acetate; In 1,4-dioxane; methanol; hexane; dichloromethane; ethyl acetate; triethylamine; N,N-dimethyl-formamide;