1-hexyn-3-yl pentafluorobenzoate

Base Information

• Chemical Name: 1-hexyn-3-yl pentafluorobenzoate
• CAS No.: 1291103-58-6
• Molecular Formula: C₁₃H₉F₅O₂
• Molecular Weight: 292.205
• Mol file: 1291103-58-6.mol

Synonyms:1-hexyn-3-yl pentafluorobenzoate

Chemical Property of 1-hexyn-3-yl pentafluorobenzoate

Chemical Property:

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Technology Process of 1-hexyn-3-yl pentafluorobenzoate

There total 1 articles about 1-hexyn-3-yl pentafluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-hexyn-3-ol (105-31-7) + pentafluorobenzoylchloride (2251-50-5) → 1-hexyn-3-yl pentafluorobenzoate (1291103-58-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol200703g

Reference yield: 78.0%

1-hexyn-3-yl pentafluorobenzoate (1291103-58-6) + methyl 3-oxo-3-phenylpropionate (614-27-7) → (R)-methyl 5-methylene-2-phenyl-4-propyl-4,5-dihydrofuran-3-carboxylate

Guidance literature:

With C₃₂H₂₇N₂P; copper(II) bis(trifluoromethanesulfonate); triethylamine; In methanol; at 20 ℃; for 15h; enantioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1002/anie.201405857

Reference yield: 72.0%

Allylbenzylamine (4383-22-6) + 1-hexyn-3-yl pentafluorobenzoate (1291103-58-6) → C16H21N

Guidance literature:

With C₃₁H₂₆N₃P; copper(II) acetate monohydrate; N-ethyl-N,N-diisopropylamine; In methanol; at -20 ℃; enantioselective reaction;

DOI:10.1039/d0ra07698h

upstream raw materials:

1-hexyn-3-ol

pentafluorobenzoylchloride

Downstream raw materials:

N-(1-hexyn-3-yl)-N,4-dimethylaniline

4-chloro-N-(1-hexyn-3-yl)-N-methylaniline

N-(R)-(hex-1-yn-3-yl)-N-methylbenzenamine