(2-Hydroxy-3-methoxyphenyl)boronic acid

Base Information

Chemical Name:(2-Hydroxy-3-methoxyphenyl)boronic acid
CAS No.:259209-17-1
Molecular Formula:C7H9 B O4
Molecular Weight:167.957
Hs Code.:2931900090
DSSTox Substance ID:DTXSID90595157
Nikkaji Number:J3.298.130E
Wikidata:Q82490102
Mol file:259209-17-1.mol

Synonyms:259209-17-1;2-Hydroxy-3-methoxyphenylboronic acid;(2-Hydroxy-3-methoxyphenyl)boronic acid;3-METHOXY-2-HYDROXYPHENYLBORONIC ACID;3-METHOXY-2-HYDROXYPHENYL BORONIC ACID;Boronic acid, B-(2-hydroxy-3-methoxyphenyl)-;SCHEMBL1492289;DTXSID90595157;BTYZWLYIOSFCJX-UHFFFAOYSA-N;AMY29891;MFCD08689552;AKOS006289760;(2-Hydroxy-3-methoxyphenyl)boronicacid;AB48276;AT35096;BS-22135;[2-hydroxy-3-(methyloxy)phenyl]boronic acid;CS-0174142;3-methoxy-2-hydroxyphenyl boronic acid, AldrichCPR

Suppliers and Price of (2-Hydroxy-3-methoxyphenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-3-methoxyphenylboronicacid
100mg
$ 45.00

SynQuest Laboratories
2-Hydroxy-3-methoxyphenylboronic acid
1 g
$ 208.00

SynQuest Laboratories
2-Hydroxy-3-methoxyphenylboronic acid
5 g
$ 768.00

Crysdot
(2-Hydroxy-3-methoxyphenyl)boronicacid 95+%
25g
$ 1756.00

Crysdot
(2-Hydroxy-3-methoxyphenyl)boronicacid 95+%
10g
$ 942.00

Crysdot
(2-Hydroxy-3-methoxyphenyl)boronicacid 95+%
1g
$ 134.00

Crysdot
(2-Hydroxy-3-methoxyphenyl)boronicacid 95+%
5g
$ 475.00

American Custom Chemicals Corporation
3-METHOXY-2-HYDROXYPHENYLBORONIC ACID 95.00%
1G
$ 240.45

Alichem
2-Hydroxy-3-methoxyphenylboronicacid
250mg
$ 720.80

Alichem
2-Hydroxy-3-methoxyphenylboronicacid
1g
$ 1836.65

Total 19 raw suppliers

Chemical Property of (2-Hydroxy-3-methoxyphenyl)boronic acid

Chemical Property:

Boiling Point:356.6±52.0 °C(Predicted)
PKA:8.18±0.58(Predicted)
PSA：69.92000
Density:1.32±0.1 g/cm3(Predicted)
LogP:-0.91940
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:168.0593889
Heavy Atom Count:12
Complexity:141

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxy-3-methoxyphenylboronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C(=CC=C1)OC)O)(O)O

Technology Process of (2-Hydroxy-3-methoxyphenyl)boronic acid

There total 2 articles about (2-Hydroxy-3-methoxyphenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: C₉H₁₃BO₅

: 259209-17-1
[2-hydroxy-3-(methyloxy)phenyl]boronic acid

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 1h;

Reference yield:

: 90-05-1
2-methoxy-phenol

: 259209-17-1
[2-hydroxy-3-(methyloxy)phenyl]boronic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 7 h / 5 - 20 °C

2.1: N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium / tert-butyl methyl ether / 6 h / -10 °C

2.2: 6 h / 20 °C

3.1: hydrogenchloride / tetrahydrofuran; water / 1 h / 20 °C

With hydrogenchloride; N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; tert-butyl methyl ether; water;

Reference yield: 98.0%

: 259209-17-1
[2-hydroxy-3-(methyloxy)phenyl]boronic acid

: 1272673-95-6
ethyl 3-amino-1-(4-bromophenyl)-1H-pyrrole-2-carboxylate hydrochloride

: 1346607-53-1
ethyl 3-amino-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-1H-pyrrole-2-carboxylate hydrochloride

Guidance literature:: [2-hydroxy-3-(methyloxy)phenyl]boronic acid; ethyl 3-amino-1-(4-bromophenyl)-1H-pyrrole-2-carboxylate hydrochloride; With caesium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; for 2h; Reflux;

With hydrogenchloride; In 1,4-dioxane; water;