Technology Process of C23H30FNO2Si
There total 4 articles about C23H30FNO2Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C17H23NO2Si; 4-flourophenylmagnesium bromide;
In
diethyl ether;
at 0 - 20 ℃;
for 2.08333h;
With
zinc(II) tetrahydroborate;
In
tetrahydrofuran; methanol; diethyl ether;
at -78 ℃;
diastereoselective reaction;
DOI:10.1055/s-0033-1340251
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran
2.1: (S)-hydroxynitrile lyase / tert-butyl methyl ether / 4 h / 0 °C / pH 5 / Enzymatic reaction
3.1: 1H-imidazole; dmap / dichloromethane / 0 - 20 °C
4.1: diethyl ether / 2.08 h / 0 - 20 °C
4.2: -78 °C
With
1H-imidazole; dmap; (S)-hydroxynitrile lyase; n-butyllithium;
In
tetrahydrofuran; diethyl ether; dichloromethane; tert-butyl methyl ether;
4.1: |Grignard Reaction;
DOI:10.1055/s-0033-1340251
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1H-imidazole; dmap / dichloromethane / 0 - 20 °C
2.1: diethyl ether / 2.08 h / 0 - 20 °C
2.2: -78 °C
With
1H-imidazole; dmap;
In
diethyl ether; dichloromethane;
2.1: |Grignard Reaction;
DOI:10.1055/s-0033-1340251