6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

Base Information

Chemical Name:6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose
CAS No.:867258-77-3
Molecular Formula:C₂₇H₄₀O₇Si
Molecular Weight:504.696
Hs Code.:

Synonyms:6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

Suppliers and Price of 6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

There total 1 articles about 6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.1%

: 677745-90-3
Benzoic acid (1R,2S,3R,5R,6R)-3-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxy-5,6-bis-methoxymethoxy-cyclohexyl ester

: 867258-77-3
6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 5h;
DOI:10.1016/j.tetasy.2005.07.010

Reference yield: 78.0%

: 867258-77-3
6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

: 100-39-0
benzyl bromide

: 867258-78-4
3,4-di-O-benzyl-6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

Guidance literature:: 6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

benzyl bromide; With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1016/j.tetasy.2005.07.010

Reference yield:

: 867258-77-3
6-O-(tert-butyldiphenyl)silyl-1,2-di-O-(methoxymethyl)-5a-carba-β-D-idopyranose

: 867258-72-8
(2R,4R,5S,6R)-2-benzoyloxy-4-(tert-butyldiphenylsilanyloxymethyl)-5,6-dibenzyloxy-cyclohexanone

Guidance literature:: Multi-step reaction with 4 steps

1.1: NaH / tetrahydrofuran / 0 - 20 °C

1.2: 78 percent / Bu₄NI / tetrahydrofuran / 24 h / 20 °C

2.1: 69 percent / molecular sieves 4 Angstroem; TMSBr / CH₂Cl₂ / 2 h / -20 °C

3.1: 91.9 percent / Et₃N; Me₂SnCl₂ / tetrahydrofuran / 6 h / 20 °C

4.1: 97.4 percent / molecular sieves 4 Angstoem; pyridinium chlorochromate / CH₂Cl₂ / 7 h / 20 °C

With trimethylsilyl bromide; 4 A molecular sieve; dimethyltin dichloride; sodium hydride; triethylamine; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetasy.2005.07.010