Technology Process of 4-(2-azidophenyl)pyridine
There total 3 articles about 4-(2-azidophenyl)pyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-(pyridin-4-yl)phenylamine;
With
acetic acid; sodium nitrite;
In
water;
at 0 ℃;
for 1.5h;
Inert atmosphere;
With
sodium azide;
In
water;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol2008268
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,4-dioxane; water / 2.5 h / 80 °C / Inert atmosphere
2.1: acetic acid; sodium nitrite / water / 1.5 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; acetic acid; sodium nitrite;
In
1,4-dioxane; water;
1.1: Suzuki cross-coupling;
DOI:10.1021/ol2008268
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,4-dioxane; water / 2.5 h / 80 °C / Inert atmosphere
2.1: acetic acid; sodium nitrite / water / 1.5 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; acetic acid; sodium nitrite;
In
1,4-dioxane; water;
1.1: Suzuki cross-coupling;
DOI:10.1021/ol2008268
