(Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: (Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 624731-39-1
• Molecular Formula: C₂₂H₂₇BO₂
• Molecular Weight: 334.266
• Mol file: 624731-39-1.mol

Synonyms:(Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of (Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 12 articles about (Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2,3-dimethyl-2,3-butane diol (76-09-5) + 2-[((E)-1,2-Diphenyl-but-1-enyl)-dimethyl-silanyl]-pyridine → (Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (624731-39-1)

Guidance literature:

2-[((E)-1,2-Diphenyl-but-1-enyl)-dimethyl-silanyl]-pyridine; With boron trichloride; In dichloromethane; at -41 ℃; for 5h;

2,3-dimethyl-2,3-butane diol; With triethylamine; In dichloromethane; at 20 ℃; for 14h;

DOI:10.1021/ja037566i

Reference yield: 82.0%

2,3-dimethyl-2,3-butane diol (76-09-5) + E-(Et)(C6H5)CC(C6H5)(SiMe2C5H4N) (624731-31-3) → (Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (624731-39-1)

Guidance literature:

E-(Et)(C₆H₅)CC(C₆H₅)(SiMe₂C₅H₄N); With boron trichloride; In dichloromethane; at -41 ℃; for 5h;

2,3-dimethyl-2,3-butane diol; With triethylamine; In dichloromethane; at 20 ℃; for 14h;

DOI:10.1002/adsc.200404220

Reference yield:

2,3-dimethyl-2,3-butane diol (76-09-5) + boron trichloride (10294-34-5) + Z-(Et)(C6H5)CC(C6H5)(SiMe2C5H4N) + E-(Et)(C6H5)CC(C6H5)(SiMe2C5H4N) (624731-31-3) → (E)-1-(4',4',5',5'-tetramethyl-1',3',2'-dioxaborolan-2'-yl)-1,2-diphenyl-1-butene (865999-25-3) + (Z)-2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (624731-39-1)

Guidance literature:

With triethylamine; In dichloromethane; alkenylsilane and BCl3 (2.2 equiv.) was employed; CH2Cl2, -40°C, 5 h; this mixt. treated with pinacol and Et3N (one-ot);

DOI:10.1021/ja037566i

upstream raw materials:

2,3-dimethyl-2,3-butane diol

E-(Et)(C₆H₅)CC(C₆H₅)(SiMe₂C₅H₄N)

iodobenzene

boron trichloride

Downstream raw materials:

(Z)-but-1-ene-1,2-diyldibenzene

cis-1,2-diphenyl-1-(4-methylphenyl)-1-butene

(E)-tamoxifen