(+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

Base Information

Chemical Name:(+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine
CAS No.:175430-87-2
Molecular Formula:C₂₄H₄₂N₂OSi
Molecular Weight:402.696
Hs Code.:

Synonyms:(+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

Suppliers and Price of (+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

There total 3 articles about (+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 100-39-0
benzyl bromide

: 175430-73-6
(2S)-1-<1'-(t-Butyldimethylsilyl)pent-2'-ylideneamino>-2-methoxymethylpyrrolidine

: 175430-87-2
(+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

Guidance literature:: With n-butyllithium; diisopropylamine; In diethyl ether; hexane; 1.) 0 deg C, 4 h; -78 deg C, 0.5 h, 2.) -78 deg C, 1 h; -78 deg C -> room temp.;

Reference yield:

: 89393-51-1
((S)-2-Methoxymethyl-pyrrolidin-1-yl)-[1-methyl-but-(Z)-ylidene]-amine

: 175430-87-2
(+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / LDA / tetrahydrofuran / 1.) 0 deg C, 4 h, 2.) -78 deg C, 1 h; -78 deg C -> room temp.

2: 88 percent / n-BuLi, diisopropylamine / diethyl ether; hexane / 1.) 0 deg C, 4 h; -78 deg C, 0.5 h, 2.) -78 deg C, 1 h; -78 deg C -> room temp.

With n-butyllithium; diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; hexane;

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 175430-87-2
(+)-(2S,2'S)-1-<2'-(t-Butyldimethylsilyl)-1'-phenylhex-3'-ylideneamino>-2-methoxymethylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / LDA / tetrahydrofuran / 1.) 0 deg C, 4 h, 2.) -78 deg C, 1 h; -78 deg C -> room temp.

2: 88 percent / n-BuLi, diisopropylamine / diethyl ether; hexane / 1.) 0 deg C, 4 h; -78 deg C, 0.5 h, 2.) -78 deg C, 1 h; -78 deg C -> room temp.

With n-butyllithium; diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; hexane;