rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate

Base Information

• Chemical Name: rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate
• CAS No.: 203852-64-6
• Molecular Formula: C₁₄H₁₅NO₄
• Molecular Weight: 261.277
• Mol file: 203852-64-6.mol

Synonyms:rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate

Chemical Property of rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate

There total 1 articles about rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

[bis(acetoxy)iodo]benzene (3240-34-4) + N-phthaloyl-DL-valine (5115-65-1,6306-53-2,6306-54-3,19506-85-5) → carbon dioxide (124-38-9,18923-20-1) + rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate (203852-64-6)

Guidance literature:

With cobalt(II) diacetate tetrahydrate; In dichloromethane; at 100 ℃; for 8h; regiospecific reaction; Green chemistry;

DOI:10.1021/acs.orglett.5b02142

Reference yield: 85.0%

rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate (203852-64-6) → (N-isobutyl)phthalimide (304-19-8)

Guidance literature:

With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; for 6h; Ambient temperature;

DOI:10.1002/hlca.19980810208

Reference yield:

rac-1-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl acetate (203852-64-6) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → C18H17NO2

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 20 ℃; for 16h;

upstream raw materials:

[bis(acetoxy)iodo]benzene

N-phthaloyl-DL-valine

Downstream raw materials:

(N-isobutyl)phthalimide