Tert-butyl N-[2-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]ethyl]carbamate

Base Information

Chemical Name:Tert-butyl N-[2-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]ethyl]carbamate
CAS No.:254100-95-3
Molecular Formula:C12H19 N3 O6
Molecular Weight:301.3
Hs Code.:
European Community (EC) Number:626-438-8
DSSTox Substance ID:DTXSID90399218
Nikkaji Number:J1.252.480C
Mol file:254100-95-3.mol

Synonyms:254100-95-3;Tert-butyl N-[2-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]ethyl]carbamate;tert-Butyl (2,5-dioxopyrrolidin-1-yl) ethane-1,2-diyldicarbamate;starbld0034107;TERT-BUTYL-N-SUCCINIMIDYL N N'-ETHYLENE-;SCHEMBL5373649;DTXSID90399218;tert-Butyl N-succinimidyl N,N'-ethylenedicarbamate;tert-Butyl N-succinimidyl N,N'-ethylenedicarbamate, >=97.0%;2-(tert-Butoxycarbonylamino)ethylcarbamic acid 2,5-dioxopyrrolizino

Suppliers and Price of Tert-butyl N-[2-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]ethyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
tert-Butyl N-succinimidyl N,N′-ethylenedicarbamate ≥97.0%
5g-f
$ 411.00

Sigma-Aldrich
tert-Butyl N-succinimidyl N,N′-ethylenedicarbamate ≥97.0%
5 g
$ 349.00

AK Scientific
tert-Butyl N-succinimidyl N,N′-ethylenedicarbamate
5g
$ 593.00

Total 3 raw suppliers

Chemical Property of Tert-butyl N-[2-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]ethyl]carbamate

Chemical Property:

Melting Point:136-141 °C
PSA：121.02000
LogP:0.64800
Storage Temp.:2-8°C
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:301.12738533
Heavy Atom Count:21
Complexity:427

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl N-succinimidyl N,N′-ethylenedicarbamate ≥97.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCNC(=O)ON1C(=O)CCC1=O

Technology Process of Tert-butyl N-[2-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]ethyl]carbamate

There total 7 articles about Tert-butyl N-[2-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]ethyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 254100-95-3
O-succinimidyl-2-(tert-butoxycarbonylamino)ethylcarbamate

Guidance literature:

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 284049-22-5
tert-butyl (2-isocyanatoethyl)carbamate

: 254100-95-3
O-succinimidyl-2-(tert-butoxycarbonylamino)ethylcarbamate

Guidance literature:: With pyridine; In toluene; at 65 ℃; for 0.0833333h;
DOI:10.1021/jo990092e

Reference yield:

: C₁₁H₁₉NO₆

: 254100-95-3
O-succinimidyl-2-(tert-butoxycarbonylamino)ethylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: NaN₃ / tetrahydrofuran; H₂O / 0.08 h / -5 °C

2: toluene / 0.17 h / 65 °C

3: 3.3 g / pyridine / toluene / 0.08 h / 65 °C

With pyridine; sodium azide; In tetrahydrofuran; water; toluene; 1: Substitution / 2: Curtius rearrangement / 3: Addition;
DOI:10.1021/jo990092e