Technology Process of 2-iodo-4-n-pentylbenzoic acid
There total 4 articles about 2-iodo-4-n-pentylbenzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium permanganate;
tetra-n-butylphosphonium chloride;
In
water; benzene;
for 3h;
Ambient temperature;
DOI:10.1021/jo00305a011
- Guidance literature:
-
With
potassium permanganate; water; tetra-n-butylphosphonium chloride;
In
benzene;
DOI:10.1039/a802902d
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2 M NaOH, NaBH4 / H2O; methanol / 0.58 h / Ambient temperature
2: 1) n-BuLi, tetramethylethylenediamine, 2) I2 / 1) petroleum ether, hexane, a) reflux, 11 h, b) room temp., 13 h, 2) -78 deg C to room temp., 1 h
3: 63 percent / KMnO4 / tetramethylphosphonium chloride / H2O; benzene / 3 h / Ambient temperature
With
sodium hydroxide; sodium tetrahydroborate; potassium permanganate; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; iodine;
tetramethylphosphonium chloride;
In
methanol; water; benzene;
DOI:10.1021/jo00305a011
