6853-57-2

Basic information

• Product Name: 4-N-PENTYLBENZALDEHYDE
• Synonyms: P-PENTYLBENZALDEHYDE;P-AMYLBENZALDEHYDE;TIMTEC-BB SBB008364;4-N-PENTYLBENZALDEHYDE;4-N-PENTYLBENZALDEHYDE / 4-N-AMYLBENZALDEHYDE;4-amylbenzaldehyde;4-n-Amylbenzaldehyde;4-Pentylbenzaldehyde
• CAS NO: 6853-57-2
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25
• EINECS: -0
• Mol File: 6853-57-2.mol
• Article Data: 13

Chemical Properties

• Melting Point: 215 °C
• Boiling Point: 142-144°C 2mm
• Flash Point: 142-144°C/2mm
• Appearance: /
• Density: 0.96 g/cm³
• Vapor Pressure: 0.00514mmHg at 25°C
• Refractive Index: 1.5215
• Sensitive: Air Sensitive
• BRN: 1869642
• CAS DataBase Reference: 4-N-PENTYLBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-PENTYLBENZALDEHYDE(6853-57-2)
• EPA Substance Registry System: 4-N-PENTYLBENZALDEHYDE(6853-57-2)

Safety Data

• Safety Statements: 24/25
• TSCA: Yes
• Hazardous Substances Data: 6853-57-2(Hazardous Substances Data)

Usage

General Description

4-N-Pentylbenzaldehyde, also known as 4-pentylbenzaldehyde or 1-pentyl-4-formylbenzene, is an aromatic chemical substance. It is a member of the class of compounds known as benzaldehydes, characterized by a benzene ring with an aldehyde substituent. 4-N-Pentylbenzaldehyde, in particular, has a pentyl group attached to the 4-position of the benzene ring and an aldehyde group attached to the 1-position. This chemical is reported to have a mild, sweet and floral scent, and is often used in fragrance and flavor applications. The molecular formula of 4-N-Pentylbenzaldehyde is C12H16O.

InChI:InChI=1/C12H16O/c1-2-3-4-5-11-6-8-12(10-13)9-7-11/h6-10H,2-5H2,1H3

Upstream product

• 49763-65-7 4-pentylbenzoyl chloride 
• 75-17-2 formaldoxime 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 18869-30-2 (E)-4,4'-dibromostilbene 
• 1809-10-5 3-bromopentane 
• 17763-69-8 4-(trifluormethanesulfonyloxy)benzaldehyde 
• 109-66-0 pentane 
• 1122-91-4 4-bromo-benzaldehyde 
• 51554-95-1 4-pentylbromobenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 627-19-0 1-Pentyne 
• 1426054-62-7 4-pent-1-ynyl-benzaldehyde 
• 1111646-87-7 C₁₄H₁₈ 

Downstream Products

• 90672-90-5 Isothiazol-5-yl-(4-pentyl-phenyl)-methanol 
• 85017-61-4 trans-β-(n-amyl)acrylic acid 
• 90863-27-7 2,5-Bis-(4-pentyl-phenyl)-[1,3]dioxane 
• 81221-36-5 2,5-Bis-(4-pentyl-phenyl)-[1,3]dioxane 
• 26311-45-5 4-pentylbenzoic acid 
• 81720-37-8 4-n-pentylbenzyl alcohol 
• 284044-50-4 4-n-Pentyl-β,β'-dibromostyrene 
• 934983-17-2 2-(4-pentyl-benzylamino)-(S)-3-phenyl-propionic acid methyl ester 
• 175136-45-5 4-pentylbenzaldehyde oxime 
• 60236-96-6 N-(4-n-Pentylbenzyliden)-4'-n-pentylanilin 

Relevant articles and documents

Azole-based non-peptidomimetic plasmepsin inhibitors

The spread of drug-resistant malaria parasites urges the search for new antimalarial drugs. Malarial aspartic proteases – plasmepsins (Plms) – are differentially expressed in multiple stages of the Plasmodium parasite's lifecycle and are considered as attractive drug targets. We report the development of novel azole-based non-peptidomimetic plasmepsin inhibitors that have been designed by bioisosteric substitution of the amide moiety in the Actelion amino-piperazine inhibitors. The best triazole-based inhibitors show submicromolar potency toward Plm II, which is comparable to that of the parent Actelion compounds. The new inhibitors can be used as a starting point for the development of a resistance-free antimalarial drug targeting the non-digestive Plm IX or X, which are essential for the malaria parasite life cycle.

SUBSTITUTED AMINOALKYLAZOLES AS MALARIAL ASPARTIC PROTEASE INHIBITORS

The present invention relates to novel aminoalkylazoles acting as inhibitors of malarial protease plasmepsin II. These can be used as medicines or as constituent of medicines for the treatment of malaria infection.

Metal-catalyzed formal amidation of alkenes under CO-free condition

An effective procedure for synthesis of amides from alkenes and [Formula presented] via Pd and Fe catalysts under mild conditions is described. A series of benzamides containing various functional groups can be obtained in reasonable yield and the possible reaction pathway is proposed in this Letter.