Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate

Base Information Edit

Chemical Name:Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS No.:253195-64-1
Molecular Formula:C11H10 F3 N O6 S
Molecular Weight:341.265
Hs Code.:
DSSTox Substance ID:DTXSID10442593
Nikkaji Number:J1.252.155C
Wikidata:Q82259953
Mol file:253195-64-1.mol

Synonyms:253195-64-1;Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate;Methyl 5-oxo-6-(trifluoromethylsulfonyloxy)-2,3-dihydro-1H-indolizine-8-carboxylate;METHYL 5-OXO-6-TRIFLUOROMETHANESULFONYLOXY-1,2,3,5-TETRAHYDROINDOLIZINE-8-CARBOXYLATE;SCHEMBL4724230;DTXSID10442593;QBJAUKHFUPLZNQ-UHFFFAOYSA-N;DIPOTASSIUMSUCCINATETRIHYDRATE;Methyl 5-oxo-6-(((trifluoromethyl)sulfonyl)oxy)-1,2,3,5-tetrahydroindolizine-8-carboxylate;Methyl5-oxo-6-(((trifluoromethyl)sulfonyl)oxy)-1,2,3,5-tetrahydroindolizine-8-carboxylate;1,2,3,5-Tetrahydro-5-oxo-6-(trifluoromethylsulfonyloxy)indolizine-8-carboxylic acid methyl ester

Suppliers and Price of Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate Edit

Chemical Property:

Melting Point:102-103 °C
Boiling Point:460.2±45.0 °C(Predicted)
PKA:-5.13±0.60(Predicted)
PSA：100.05000
Density:1 +-.0.1 g/cm3(Predicted)
LogP:1.89030
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:341.01809270
Heavy Atom Count:22
Complexity:686

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C2CCCN2C(=O)C(=C1)OS(=O)(=O)C(F)(F)F

Technology Process of Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate

There total 4 articles about Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 37595-74-7
N,N-phenylbistrifluoromethane-sulfonimide

: 185198-42-9
6-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid methyl ester

: 253195-64-1
methyl 5-oxo-6-trifluoromethanesulfonyloxy-1,2,3,5-tetrahydroindolizine-8-carboxylate

Guidance literature:: 6-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid methyl ester; With triethylamine; In dichloromethane; at 0 ℃; for 0.333333h;

N,N-phenylbistrifluoromethane-sulfonimide; In dichloromethane; at 20 ℃; for 6h;