(5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene

Base Information

• Chemical Name: (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene
• CAS No.: 548485-25-2
• Molecular Formula: C₃₅H₄₅BrO₉
• Molecular Weight: 689.641

Synonyms:(5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene

Chemical Property of (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene

There total 4 articles about (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

penta(ethylene glycol) bis(p-toluenesulfonate) (41024-91-3) + 5-bromo-1,3-bis[(4S)-4-hydroxy-4-phenyl-2-oxobutyl]-2-methoxybenzene (497107-20-7) → (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1(29),26(30),27-triene (548485-25-2)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 60 ℃;

DOI:10.1016/S0957-4166(03)00031-4

Reference yield:

5-bromo-1,3-bis(bromomethyl)-2-methoxybenzene (118249-11-9) → (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1(29),26(30),27-triene (548485-25-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaH / tetrahydrofuran / 3 h / Heating

1.2: tetrahydrofuran / 6 h / Heating

2.1: 14.9 g / pyridinium p-toluenesulfonate / ethanol / 12 h / 50 °C

3.1: 25 percent / NaH / tetrahydrofuran / 60 °C

With pyridinium p-toluenesulfonate; sodium hydride; In tetrahydrofuran; ethanol;

DOI:10.1016/S0957-4166(03)00031-4

Reference yield:

(S)-(+)-2-phenyl-2-(tetrahydropyranyloxy)ethanol (94199-20-9) → (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1(29),26(30),27-triene (548485-25-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaH / tetrahydrofuran / 3 h / Heating

1.2: tetrahydrofuran / 6 h / Heating

2.1: 14.9 g / pyridinium p-toluenesulfonate / ethanol / 12 h / 50 °C

3.1: 25 percent / NaH / tetrahydrofuran / 60 °C

With pyridinium p-toluenesulfonate; sodium hydride; In tetrahydrofuran; ethanol;

DOI:10.1016/S0957-4166(03)00031-4

upstream raw materials:

penta(ethylene glycol) bis(p-toluenesulfonate)

5-bromo-1,3-bis[(4S)-4-hydroxy-4-phenyl-2-oxobutyl]-2-methoxybenzene

5-bromo-1,3-bis(bromomethyl)-2-methoxybenzene

(S)-(+)-2-phenyl-2-(tetrahydropyranyloxy)ethanol

Downstream raw materials:

(5S,22S)-30-hydroxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene

(5S,22S)-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 548485-25-2 (5S,22S)-8-bromo-30-methoxy-5,22-diphenyl-3,6,9,12,15,18,21,24-octaoxabicyclo[24.3.1]triaconta-1⁽²⁹⁾,26⁽³⁰⁾,27-triene

Send

Send

Metric Ton KG G Pound L ML

Send

Send