94199-20-9

Upstream product

• 17199-29-0 (S)-Mandelic acid 
• 155486-11-6 (S)-Phenyl-[(tetrahydro-pyran-2-yloxy)]-acetic acid methyl ester 
• 21210-43-5 (S)-Methyl mandelate 
• 33973-12-5 (S)-(+)-methyl 2-phenyl-2-(tetrahydropyranyloxy)acetate 
• 20698-91-3 (R)-methyl mandelate 
• 611-71-2 (R)-Mandelic Acid 
• 110-87-2 3,4-dihydro-2H-pyran 
• 13704-09-1 (S)-(-)-ethyl mandelate 
• 133867-57-9 (R)-Phenyl-[(tetrahydro-pyran-2-yloxy)]-acetic acid methyl ester 
• 33973-12-5 R-(-)-methyl 2-phenyl-2-(tetrahydropyranyloxy)acetate 
• 27373-43-9 (S)-Phenyl-[(tetrahydro-pyran-2-yloxy)]-acetic acid tetrahydro-pyran-2-yl ester 

Downstream Products

• 93417-22-2 C₃₀H₄₂O₇ 
• 121917-51-9 (R,R)-(-)-1,11-diphenyl-3,6,9-trioxaundecane-1,11-diol 
• 497107-20-7 5-bromo-1,3-bis[(4S)-4-hydroxy-4-phenyl-2-oxobutyl]-2-methoxybenzene 
• 199992-19-3 (5S,8S,10S,13S)-8,10-Dimethyl-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17-diene-19,21-dione 
• 188303-42-6 (5S,8S,10S,13S)-19-Methoxy-8,10-dimethyl-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-trien-21-ol 
• 188303-41-5 (5S,8S,10S,13S)-19,21-Dimethoxy-8,10-dimethyl-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-triene 
• 109183-66-6 (R)-(+)-2-phenyl-2-(tetrahydropyranyloxy)ethyl p-toluenesulfonate 
• 109183-66-6 (S)-2-phenyl-2-tetrahydropyranyloxy-1-p-toluenesulfonyloxyethane 
• 133811-88-8 (4R,14R)-(-)-4,14-diphenyl-3,6,9,12,15-pentaoxa-21-azabicyclo<15.3.1>heneicosa-1(21),17,19-triene 
• 109183-67-7 (R)-(+)-2-phenyl-2-(tetrahydropyranyloxy)ethyl p-tolyl sulfide 
• 105769-52-6 (R)-(+)-2-chloro-2-phenylethyl p-methoxyphenyl sulfone 
• 675576-60-0 (R)-2-(4-Methoxy-benzenesulfonyl)-1-phenyl-ethanol 
• 105769-50-4 (R)-(+)-2-chloro-2-phenylethyl p-chlorophenyl sulfone 

Relevant academic research and scientific papers

Zirconium cation coordination in the borohydride-mediated synthesis of β-hydroxy-N-alkoxylamines

Hydride reductions of oxime ethers to hydroxylamine derivatives are facilitated by the participation of neighboring hydroxyl groups. Precomplexation with zirconium cation in ether-methylene chloride solutions is effective for selective C=N bond reduction. The course for stereochemical control is dictated by Lewis acid coordination complexes of E- and Z-oximino ethers which lead to the preferred diastereofacial delivery of external hydride.

Asymmetric Diels-Alder reactions of enantiopure 1-methoxy-3-(phenyl-2- hydroxyethylsulfinyl)-1,3-butadienes

Enantiopure 1-methoxy-3-(1-phenyl- and 2-phenyl-2-hydroxyethylsulfinyl)- 1,3-butadienes were prepared from ethyl mandelate. Diels-Alder reactions with methyl acrylate proceeded with complete regioselectivity and high diastereoselectivity.

Enantioselective Protonation of Samarium Enolates by a C2-Symmetric Chiral Diol

High enantioselectivity (up to 97percentee) have been achieved in the protonation of samarium enolates which were generated by SmI2-mediated cross-coupling reaction between unsymmetrical dialkylketene and allyl iodide, using, using a C2-symmetr

Recognition by New Symmetrically Substituted Chiral Diphenyl- and Di-tert-butylpyridino-18-crown-6 and Asymmetrically Substituted Chiral Dimethylpyridino-18-crown-6 Ligands of the Enantiomers of Various Organic Ammonium Perchlorates

Three new chiral pyridino-18-crown-6 ligands have been prepared.These ligands contain either two phenyl, two tert-butyl, or two methyl substituents on chiral macroring carbon atoms.The chiral di-tert-butyl-substituted diester crown analogue was also prepared.The starting chiral di-tert-butyl-substituted tetraethylene glycol needed to prepare the two di-tert-butyl-substituted crowns was obtained from chiral tert-butyl-1,2-ethanediol, which was resolved from its bis(hydrogen phthalate) brucine salt.A high degree of chiral recognition in CD2Cl2 of the enantiomers of ammonium perchlorate (NapEt) was shown by the diphenyl- and di-tert-butyl-substituted crowns as measured by differences in the free energy of avtivation (ΔGc*) values determined by temperature dependent 1H NMR spectroscopy.The diphenyl- and di-tert-butyl-substituted crowns also exhibited high chiral recognition for the enantiomers of NapEt and other chiral organic ammonium salts in methanol and methanol-chloroform mixtures as shown by a large difference in the log K values determined by a direct 1H NMR technique.

Asymmetric Radical Reaction in the Coordination Sphere. 2. Asymmetric Addition of Alkane- and Arenesulfonyl Chlorides to Olefins Catalyzed by a Ruthenium(II)-Phosphine Complex with Chiral Ligands

The addition of arenesulfonyl chlorides to styrene in the presence of a catalytic amount of a ruthenium(II) complex with chiral phosphine ligands, Ru2Cl43 or Ru2Cl43, proceeds under mild conditions to give optically active 1:1 adducts,

The Preparation of New Chiral Diphenyl-Substituted Macrocyclic Polyether-Diester Compounds and their Enantiomeric Recognition of Chiral Organic Ammonium Salts

A series of chiral diphenyl-substituted macrocyclic polyether-diester ligands have been prepared from the chiral diphenyl-substituted tetraethylene glycol.Enantiomeric recognition by the chiral diphenyl-sunstituted pyridino-diester-18-crown-6 compound (7)