Ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate

Base Information

Chemical Name:Ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate
CAS No.:35051-50-4
Molecular Formula:C₁₁H₂₃O₅P
Molecular Weight:266.274
Hs Code.:
DSSTox Substance ID:DTXSID50472415
Nikkaji Number:J430.652J
Mol file:35051-50-4.mol

Synonyms:35051-50-4;ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate;2-(DIETHOXYPHOSPHINYL)-3-METHYLBUTANOIC ACID ETHYL ESTER;ethyl 2-diethoxyphosphoryl-3-methylbutanoate;Butanoic acid,2-(diethoxyphosphinyl)-3-methyl-, ethyl ester;2-Phosphono-3-(methylbutyric Acid) Triethyl Ester;Butanoic acid, 2-(diethoxyphosphinyl)-3-methyl-, ethyl ester;Ethyl 2-diethoxyphosphoryl-3-methyl-butanoate;SCHEMBL3163528;DTXSID50472415;FJELRNPBKJSTOQ-UHFFFAOYSA-N;MFCD07778463;AKOS015994924;ethyl 2-diethylphosphono-3-methylbutanoate;CS-0159649;FT-0769106;A902545;diethyl 1-ethoxycarbonyl-2-methylpropyl phosphonate;J-520642;Diethyl [1-(ethoxycarbonyl)-2-methylpropyl]phosphonate;2-(diethoxy-phosphoryl)-3-methyl-butyric acid ethyl ester

Suppliers and Price of Ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Phosphono-3-(methylbutyricAcid)TriethylEster
2.5g
$ 85.00

American Custom Chemicals Corporation
DIETHYL[1-(ETHOXYCARBONYL)-2-METHYLPROPYL]PHOSPHONATE 95.00%
5MG
$ 505.88

Total 10 raw suppliers

Chemical Property of Ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate

Chemical Property:

Boiling Point:102-104 °C(Press: 0.4 Torr)
PSA：71.64000
Density:1.059±0.06 g/cm3(Predicted)
LogP:2.84020
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:266.12831083
Heavy Atom Count:17
Complexity:267

Purity/Quality:

97% ^*data from raw suppliers

2-Phosphono-3-(methylbutyricAcid)TriethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(C)C)P(=O)(OCC)OCC
Uses 2-Phosphono-3-(methylbutyric Acid) Triethyl Ester is an intermediate in the synthesis of (+)-amabiline, an unsaturated pyrrolizidine alkaloid from Cynoglossum amabile.

Technology Process of Ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate

There total 8 articles about Ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

: 75-30-9
2-iodo-propane

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 148515-21-3,35051-50-4
ethyl 2-(diethoxyphosphoryl)-3-methylbutyrate

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With potassium tert-butylate; In dimethyl sulfoxide; at 0 ℃; for 0.5h;

2-iodo-propane; In dimethyl sulfoxide; at 60 ℃; for 1.5h;
DOI:10.1021/acs.jmedchem.1c00621