N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

Base Information

Chemical Name:N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide
CAS No.:216985-29-4
Molecular Formula:C₁₆H₁₀FNO₃
Molecular Weight:283.259
Hs Code.:

Synonyms:N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

Suppliers and Price of N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

Chemical Property:

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Technology Process of N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

There total 6 articles about N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 531-81-7
2-oxo-2H-chromene-3-carboxylic acid

: 371-40-4
4-fluoroaniline

: 216985-29-4
N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

Guidance literature:: 2-oxo-2H-chromene-3-carboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 0.5h;

4-fluoroaniline; With triethylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.2174/1570180816666190617150803

Reference yield:

: 886124-83-0
C₁₃H₈N₂O₃

: 371-40-4
4-fluoroaniline

: 216985-29-4
N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

Guidance literature:: In acetonitrile; at 20 ℃; for 16h;
DOI:10.2174/1573406413666170623083116

Reference yield:

: 531-81-7
2-oxo-2H-chromene-3-carboxylic acid

: 216985-29-4
N-(4-fluorophenyl)-2-oxo-2H-chromene-3-carboxaniide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / acetonitrile / 0.5 h / 20 °C

2: acetonitrile / 16 h / 20 °C

With triethylamine; In acetonitrile;
DOI:10.2174/1573406413666170623083116