1-(4-Methoxyphenyl)-1-chlorosilacyclobutane

Base Information

• Chemical Name: 1-(4-Methoxyphenyl)-1-chlorosilacyclobutane
• CAS No.: 251453-07-3
• Molecular Formula: C10H13 Cl O Si
• Molecular Weight: 212.751
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID80450908
• Nikkaji Number: J1.336.191F
• Wikidata: Q82270747
• Mol file: 251453-07-3.mol

Synonyms:251453-07-3;1-chloro-1-(4-methoxyphenyl)siletane;1-(4-METHOXYPHENYL)-1-CHLOROSILACYCLOBUTANE;Silacyclobutane, 1-chloro-1-(4-methoxyphenyl)-;SCHEMBL6435039;DTXSID80450908;1-Chloro-1-(4-methoxyphenyl)silacyclobutane

Chemical Property of 1-(4-Methoxyphenyl)-1-chlorosilacyclobutane

Chemical Property:

• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.528
• Boiling Point: 100°C/0/1mmHg
• Flash Point: 100.983°C
• PSA: 9.23000
• Density: 1.119g/cm³
• LogP: 2.49020
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 212.0424193
• Heavy Atom Count: 13
• Complexity: 174

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)[Si]2(CCC2)Cl

Technology Process of 1-(4-Methoxyphenyl)-1-chlorosilacyclobutane

There total 1 articles about 1-(4-Methoxyphenyl)-1-chlorosilacyclobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1,1-dichlorosilacyclobutane (2351-33-9) + 4-methoxyphenyl magnesium bromide (13139-86-1) → 1-chloro-1-(4'-methoxyphenyl)silacyclobutane (251453-07-3)

Guidance literature:

In diethyl ether; at 0 - 20 ℃;

DOI:10.1021/ol991054k

Reference yield: 91.0%

1-chloro-1-(4'-methoxyphenyl)silacyclobutane (251453-07-3) + iodobenzene (591-50-4) → 4-methoxylbiphenyl (613-37-6)

Guidance literature:

1-chloro-1-(4'-methoxyphenyl)silacyclobutane; With tetrabutyl ammonium fluoride; In tetrahydrofuran;

iodobenzene; With tri-tert-butyl phosphine; tetrabutyl ammonium fluoride; bis(η3-allyl-μ-chloropalladium(II)); In tetrahydrofuran; for 1h; Further stages.; Heating;

DOI:10.1021/ol991054k

Reference yield: 85.0%

1-chloro-1-(4'-methoxyphenyl)silacyclobutane (251453-07-3) + 1-Iodonaphthalene (90-14-2) → 1-(4-methoxyphenyl)naphthalene (27331-33-5)

Guidance literature:

1-chloro-1-(4'-methoxyphenyl)silacyclobutane; With tetrabutyl ammonium fluoride; In tetrahydrofuran;

1-Iodonaphthalene; With tri-tert-butyl phosphine; tetrabutyl ammonium fluoride; bis(η3-allyl-μ-chloropalladium(II)); In tetrahydrofuran; for 2h; Further stages.; Heating;

DOI:10.1021/ol991054k

upstream raw materials:

1,1-dichlorosilacyclobutane

4-methoxyphenyl magnesium bromide

Downstream raw materials:

1-(4'-methoxy-biphenyl-4-yl)-ethanone

4-methoxy-4'-nitrobiphenyl

4'-methoxybiphenyl-4-carbonitrile

4-(4-tolyl)anisole