Pyrrolo[1,2-c]pyrimidine, 1-methyl- (9CI)

Base Information

Chemical Name:Pyrrolo[1,2-c]pyrimidine, 1-methyl- (9CI)
CAS No.:251102-35-9
Molecular Formula:C₈H₈N₂
Molecular Weight:132.165
Hs Code.:
Mol file:251102-35-9.mol

Synonyms:1-Methylpyrrolo[1,2-c]pyrimidine

Suppliers and Price of Pyrrolo[1,2-c]pyrimidine, 1-methyl- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1-methyl-Pyrrolo[1,2-c]pyrimidine 97.00%
25G
$ 13300.00

AccelPharmtech
1-methyl-Pyrrolo[1,2-c]pyrimidine 97.00%
5G
$ 5360.00

Total 1 raw suppliers

Chemical Property of Pyrrolo[1,2-c]pyrimidine, 1-methyl- (9CI)

Chemical Property:

PSA：17.30000
LogP:1.64270

Purity/Quality:: 1-methyl-Pyrrolo[1,2-c]pyrimidine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Pyrrolo[1,2-c]pyrimidine, 1-methyl- (9CI)

There total 3 articles about Pyrrolo[1,2-c]pyrimidine, 1-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 274-43-1
pyrrole<1,2-c>pyrimidine

: 74-88-4
methyl iodide

: 251102-35-9
1-methylpyrrolo[1,2-c]pyrimidine

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 14h;
DOI:10.1021/jo9907080

Reference yield:

: 70380-76-6
3-[(4-methylphenyl)sulfonyl]pyrrolo[1,2-c]pyrimidine

: 251102-35-9
1-methylpyrrolo[1,2-c]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / Na₂HPO₄; sodium amalgam / methanol / 3 h / 20 °C

2: 39 percent / LDA / tetrahydrofuran / 14 h / -78 °C

With disodium hydrogenphosphate; sodium amalgam; lithium diisopropyl amide; In tetrahydrofuran; methanol; 1: desulfonylation / 2: Methylation;
DOI:10.1021/jo9907080

Reference yield:

: 251102-35-9
1-methylpyrrolo[1,2-c]pyrimidine

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In 1,2-dimethoxyethane; at 120 ℃; for 2h; Microwave irradiation; Inert atmosphere;