Technology Process of (1S,2S)-1,2-bis(4-nitrophenyl)ethane-1,2-diol
There total 2 articles about (1S,2S)-1,2-bis(4-nitrophenyl)ethane-1,2-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate; potassium hexacyanoferrate(III);
In
water; tert-butyl alcohol;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/ol501012f
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium tert-butylate / tetrahydrofuran; tert-butyl alcohol / 26 h / 0 - 20 °C / Inert atmosphere
2: potassium carbonate; potassium hexacyanoferrate(III) / tert-butyl alcohol; water / 20 °C / Inert atmosphere
With
potassium tert-butylate; potassium carbonate; potassium hexacyanoferrate(III);
In
tetrahydrofuran; water; tert-butyl alcohol;
2: |Sharpless Dihydroxylation;
DOI:10.1021/ol501012f
- Guidance literature:
-
(1S,2S)-1,2-bis(4-nitrophenyl)ethane-1,2-diol;
With
oxygen; sodium t-butanolate;
In
tetrahydrofuran;
at 20 ℃;
for 2h;
under 760.051 Torr;
With
hydrogenchloride;
In
tetrahydrofuran; water;
pH=1;
chemoselective reaction;
DOI:10.1021/ol501012f
