736-31-2

Basic information

• Product Name: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE)
• Synonyms: Ccris 8546;Einecs 212-002-0;(E)-p,p'-Dinitrostilbene;(E)-4,4'-Dinitrostilbene;Stilbene, 4,4'-dinitro-, (E)-;1,1'-(E)-ethene-1,2-diylbis(4-nitrobenzene);(E)-1,1'-(1,2-Ethenediyl)bis(4-nitrobenzene);1,1'-[(E)-1,2-Ethenediyl]bis(4-nitrobenzene);Benzene, 1,1'-(1E)-1,2-ethenediylbis[4-nitro-;1-nitro-4-[(E)-2-(4-nitrophenyl)ethenyl]benzene
• CAS NO: 736-31-2
• Molecular Formula: C₁₄H₁₀N₂O₄
• Molecular Weight: 270.24
• EINECS: 212-002-0
• Mol File: 736-31-2.mol
• Article Data: 66

Chemical Properties

• Melting Point: 288 °C
• Boiling Point: 394.6°Cat760mmHg
• Flash Point: 182.7°C
• Appearance: /
• Density: 1.376g/cm³
• Refractive Index: 1.6500 (estimate)
• CAS DataBase Reference: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) (CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) (736-31-2)
• EPA Substance Registry System: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) (736-31-2)

Safety Data

• Hazardous Substances Data: 736-31-2(Hazardous Substances Data)

Usage

General Description

The chemical (E)-1,1’-(1,2-ethenediyl)bis(4-nitrobenzene) is a compound with the molecular formula C14H10N4O4. It is a yellow crystalline solid that is insoluble in water but soluble in organic solvents. (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) is commonly used as an intermediate in the synthesis of various organic compounds and dyes. It is also used in the production of pharmaceuticals and agrochemicals. In addition, (E)-1,1’-(1,2-ethenediyl)bis(4-nitrobenzene) may have potential applications in the field of materials science, particularly in the development of new functional materials. It is important to handle this chemical with care, as it is toxic and can cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 736-30-1 1,2-bis(4-nitrophenyl)ethane 
• 588-59-0 stilbene 
• 873420-19-0 α'-iodo-4,4'-dinitro-bibenzyl-α-ol 
• 121986-07-0 p-nitromandelonitrile 
• 1530-42-3 (4-nitrobenzyl)triphenylphosphonium chloride 
• 619-78-3 1-dichloromethyl-4-nitrobenzene 
• 100-14-1 4-nitrobenzyl chloride 
• 4025-75-6 (4-nitrophenyl)methanesulfonyl chloride 
• 6933-17-1 (4-nitrobenzylidene)triphenylphosphorane 
• 78-08-0 Triethoxyvinylsilane 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 91-22-5 quinoline 
• 6277-62-9 2,3t-bis-(4-nitro-phenyl)-acrylic acid 
• 2767-70-6 (p-nitrobenzyl)triphenylphosphonium bromide 

Downstream Products

• 619-93-2 (Z)-4,4'-dinitrostilbene 
• 105222-70-6 α,α'-dichloro-4,4'-dinitro-bibenzyl 
• 93968-39-9 meso-1,2-dibromo-1,2-di(4-nitrophenyl)-2-ethane 
• 13190-56-2 4,4'-ethanediyl-bis-cyclohexylamine 
• 7314-06-9 (E)-4,4'-diaminostilbene 
• 7297-52-1 nitroaminostilbene 
• 621-95-4 4,4'-diaminodihydrostilbene 
• 621-96-5 4,4'-diaminostilbene 
• 99-99-0 1-methyl-4-nitrobenzene 
• 62-23-7 4-nitro-benzoic acid 
• 886225-57-6 N-(4-{2-[4-(hydroxyoxalyl-amino)-phenyl]-vinyl}-phenyl)-oxalamic acid 
• 886225-56-5 N-(4-{2-[4-(ethoxyoxalyl-amino)-phenyl]-vinyl}-phenyl)-oxalamic acid ethyl ester 
• 659-22-3 trans-4,4'-dihydroxystilbene 
• 2735-14-0 1,2-bis(4-nitrophenyl)acetylene 

Relevant articles and documents

Single-molecule conductance in a unique cross-conjugated tetra(aminoaryl)ethene

A 1,1,2,2-tetrakis(4-aminophenyl)ethene with three paths of π-conjugation, linear-cis, linear-trans and a cross-conjugation, has been prepared. The molecule is able to bind to gold electrodes forming molecular junctions for single-molecule conductance measurements. Only two regimes of conduction are found experimentally. The modelling of the conductance allows to assign them to through-bond transmission in the linear case, while the cross-conjugated channel is further assisted by through-space transmission, partially alleviating the destructive quantum interference. This journal is

Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus

Antibiotic resistance remains a major global public health threat that requires sustained discovery of novel antibacterial agents with unexploited scaffolds. Structure-activity relationship of the first-generation aryl isonitrile compounds we synthesized led to an initial lead molecule that informed the synthesis of a second-generation of aryl isonitriles. From this new series of 20 compounds, three analogues inhibited growth of methicillin-resistant Staphylococcus aureus (MRSA) (from 1 to 4 μM) and were safe to human keratinocytes. Compound 19, with an additional isonitrile group exhibited improved activity against MRSA compared to the first-generation lead compound. This compound emerged as a candidate worthy of further investigation and further reinforced the importance of the isonitrile functionality in the compounds’ anti-MRSA activity. In a murine skin wound model, 19 significantly reduced the burden of MRSA, similar to the antibiotic fusidic acid. In summary, 19 was identified as a new lead aryl isonitrile compound effective against MRSA.