cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

Base Information

Chemical Name:cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt
CAS No.:1352834-09-3
Molecular Formula:C₇H₁₀O₂*C₈H₁₁N
Molecular Weight:247.337
Hs Code.:

Synonyms:cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

Suppliers and Price of cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

There total 1 articles about cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.9%

: 4771-80-6
1,2,5,6-tetrahydrobenzoic acid

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 1352834-09-3
cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

Guidance literature:: In acetone; at 55 - 60 ℃; for 2.83333h; Reflux;

Reference yield:

: 1352834-09-3
cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

: 14-O-{[(1S,2S,4S)-4-tert-butoxycarbonylamino-2-hydroxy-cyclohexyl-sulfanyl]-acetyl}-mutilin

Guidance literature:: Multi-step reaction with 7 steps

1.1: acetone / 0.25 h / Reflux; Resolution of racemate

2.1: hydrogenchloride / water; tert-butyl methyl ether / 0.25 h / 20 - 25 °C

3.1: triethylamine; diphenyl phosphoryl azide / toluene; tert-butyl alcohol / 0.25 h / 20 - 60 °C

3.2: 0.83 h / 50 °C

4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.5 h / 30 - 40 °C / Cooling with ice

5.1: toluene / 15 - 25 °C

5.2: 30 °C

5.3: 40 - 45 °C

6.1: hydrazine hydrate; diothiothreitol / dichloromethane / 0.42 h / 15 - 25 °C / Inert atmosphere

6.2: 0.48 h

7.1: sodium hydroxide / benzyltri(n-butyl)ammonium chloride / water; tert-butyl methyl ether / 0.08 h / 20 - 25 °C / Inert atmosphere

With hydrogenchloride; diphenyl phosphoryl azide; hydrazine hydrate; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; diothiothreitol; benzyltri(n-butyl)ammonium chloride; In dichloromethane; tert-butyl methyl ether; water; acetone; toluene; tert-butyl alcohol; 3.1: Curtius Rearrangement;

Reference yield:

: 1352834-09-3
cyclohex-3-ene-1-carboxylic acid (R)-(+)-1-phenylethanamine salt

: 1061337-55-0
14-O-{[(1S,2S,4S)-4-amino-2-hydroxy-cyclohexylsulfanyl]-acetyl}-mutilin

Guidance literature:: Multi-step reaction with 8 steps

1.1: acetone / 0.25 h / Reflux; Resolution of racemate

2.1: hydrogenchloride / water; tert-butyl methyl ether / 0.25 h / 20 - 25 °C

3.1: triethylamine; diphenyl phosphoryl azide / toluene; tert-butyl alcohol / 0.25 h / 20 - 60 °C

3.2: 0.83 h / 50 °C

4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.5 h / 30 - 40 °C / Cooling with ice

5.1: toluene / 15 - 25 °C

5.2: 30 °C

5.3: 40 - 45 °C

6.1: hydrazine hydrate; diothiothreitol / dichloromethane / 0.42 h / 15 - 25 °C / Inert atmosphere

6.2: 0.48 h

7.1: sodium hydroxide / benzyltri(n-butyl)ammonium chloride / water; tert-butyl methyl ether / 0.08 h / 20 - 25 °C / Inert atmosphere

8.1: phosphoric acid / isopropyl alcohol / 35 - 50 °C

With hydrogenchloride; phosphoric acid; diphenyl phosphoryl azide; hydrazine hydrate; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; diothiothreitol; benzyltri(n-butyl)ammonium chloride; In dichloromethane; tert-butyl methyl ether; water; isopropyl alcohol; acetone; toluene; tert-butyl alcohol; 3.1: Curtius Rearrangement;