Technology Process of (E)-N-((5-iodo-1-methyl-1H-indol-3-yl)methylene)-4-methylbenzenesulfonamide
There total 4 articles about (E)-N-((5-iodo-1-methyl-1H-indol-3-yl)methylene)-4-methylbenzenesulfonamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
rhodium (II) octanoate dimer;
In
1,2-dichloro-ethane;
at 60 ℃;
for 4h;
Inert atmosphere;
DOI:10.1021/ol501618z
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 0 - 20 °C / Inert atmosphere
2: copper(I) thiophene-2-carboxylate / toluene / 2 h / 20 °C / Inert atmosphere
3: rhodium (II) octanoate dimer / 1,2-dichloro-ethane / 4 h / 60 °C / Inert atmosphere
With
copper(I) thiophene-2-carboxylate; rhodium (II) octanoate dimer; potassium carbonate;
In
1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol501618z
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / toluene; dichloromethane / 14 h / 0 - 20 °C / Inert atmosphere
2: potassium carbonate / N,N-dimethyl-formamide / 4 h / 0 - 20 °C / Inert atmosphere
3: copper(I) thiophene-2-carboxylate / toluene / 2 h / 20 °C / Inert atmosphere
4: rhodium (II) octanoate dimer / 1,2-dichloro-ethane / 4 h / 60 °C / Inert atmosphere
With
copper(I) thiophene-2-carboxylate; rhodium (II) octanoate dimer; potassium carbonate;
In
dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol501618z
