(2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine

Base Information

Chemical Name:(2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine
CAS No.:1258232-68-6
Molecular Formula:C₂₄H₂₂Br₂FNO₂
Molecular Weight:535.251
Hs Code.:

Synonyms:(2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine

Suppliers and Price of (2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine

Chemical Property:

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Technology Process of (2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine

There total 2 articles about (2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1258232-67-5
(2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)pyrrolidine-3,4-diol

: 1258232-68-6
(2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine

Guidance literature:: In tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 5467-74-3
4-Bromophenylboronic acid

: 1258232-68-6
(2S,3R,4R,5S)-2,5-bis(4-bromophenyl)-1-(4-fluorophenyl)-3,4-dimethoxypyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: iodobenzene diacetic acid / methanol-dichloromethane; aq. sulfuric acid; ethanol; ethyl acetate

2: tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide; mineral oil

With iodobenzene diacetic acid; In tetrahydrofuran; methanol-dichloromethane; aq. sulfuric acid; ethanol; ethyl acetate; N,N-dimethyl-formamide; mineral oil;