1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

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Chemical Name:1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil
CAS No.:1241387-96-1
Molecular Formula:C₄₀H₄₂N₄O₁₁
Molecular Weight:754.794
Hs Code.:

Synonyms:1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

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Chemical Property of 1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

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Technology Process of 1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

There total 1 articles about 1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1241387-94-9
1-(2-O-{[1-(5-(azidomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

: 1241387-96-1
1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

Guidance literature:: With water; triphenylphosphine; In tetrahydrofuran; Reflux;
DOI:10.1021/ol101489v

Reference yield: 89.0%

: 874944-64-6
6-(1-N-(4,4'-dimethoxytrityl)-D-(+)-biotinoyl)aminohexanoic acid

: 1241387-96-1
1-(2-O-{[1-(5-(aminomethyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

: 1241387-99-4
1-(2-O-{[1-(5-(({6-N-[1-(4,4'-dimethoxytrityl)-D-biotinoyl]aminohexanoyl}amino)methyl)-2-nitrophenyl)ethoxy]methyl}-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;
DOI:10.1021/ol101489v